Cargando…

Role of Nrf2 in Pancreatic Cancer

Pancreatic tumors are a serious health problem with a 7% mortality rate worldwide. Inflammatory processes and oxidative stress play important roles in the development of pancreatic diseases/cancer. To maintain homeostasis, a balance between free radicals and the antioxidant system is essential. Nucl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cykowiak, Marta, Krajka-Kuźniak, Violetta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773052/ https://www.ncbi.nlm.nih.gov/pubmed/35052602 http://dx.doi.org/10.3390/antiox11010098

Ejemplares similares

Attenuation of Pancreatic Cancer In Vitro and In Vivo via Modulation of Nrf2 and NF-κB Signaling Pathways by Natural Compounds
por: Cykowiak, Marta, et al.
Publicado: (2021)

Comparison of the Impact of Xanthohumol and Phenethyl Isothiocyanate and Their Combination on Nrf2 and NF-κB Pathways in HepG2 Cells In Vitro and Tumor Burden In Vivo
por: Cykowiak, Marta, et al.
Publicado: (2021)

Modulation of Nrf2 and NF-κB Signaling Pathways by Naturally Occurring Compounds in Relation to Cancer Prevention and Therapy. Are Combinations Better Than Single Compounds?
por: Krajka-Kuźniak, Violetta, et al.
Publicado: (2021)

R-sulforaphane modulates the expression profile of AhR, ERα, Nrf2, NQO1, and GSTP in human breast cell lines
por: Licznerska, Barbara, et al.
Publicado: (2020)

(+)-Usnic acid modulates the Nrf2-ARE pathway in FaDu hypopharyngeal carcinoma cells
por: Krajka-Kuźniak, Violetta, et al.
Publicado: (2021)

Unlocking the Potential: Novel NSAIDs Hybrids Unleash Chemopreventive Power toward Liver Cancer Cells through Nrf2, NF-κB, and MAPK Signaling Pathways
por: Narożna, Maria, et al.
Publicado: (2023)

The synthesis of novel thioderivative chalcones and their influence on NF-κB, STAT3 and NRF2 signaling pathways in colorectal cancer cells
por: Papierska, Katarzyna, et al.
Publicado: (2022)

Anti-Cancer Potential of Synthetic Oleanolic Acid Derivatives and Their Conjugates with NSAIDs
por: Baer-Dubowska, Wanda, et al.
Publicado: (2021)

The Effect of Novel Oleanolic Acid Oximes Conjugated with Indomethacin on the Nrf2-ARE And NF-κB Signaling Pathways in Normal Hepatocytes and Human Hepatocellular Cancer Cells
por: Narożna, Maria, et al.
Publicado: (2020)

The effect of resveratrol and its methylthio-derivatives on the Nrf2-ARE pathway in mouse epidermis and HaCaT keratinocytes
por: Krajka-Kuźniak, Violetta, et al.
Publicado: (2014)

Indomethacin and Diclofenac Hybrids with Oleanolic Acid Oximes Modulate Key Signaling Pathways in Pancreatic Cancer Cells
por: Narożna, Maria, et al.
Publicado: (2022)

Lichen-Derived Depsides and Depsidones Modulate the Nrf2, NF-κB and STAT3 Signaling Pathways in Colorectal Cancer Cells
por: Papierska, Katarzyna, et al.
Publicado: (2021)

Lichen-derived caperatic acid and physodic acid inhibit Wnt signaling in colorectal cancer cells
por: Paluszczak, Jarosław, et al.
Publicado: (2017)

Conjugation of Diclofenac with Novel Oleanolic Acid Derivatives Modulate Nrf2 and NF-κB Activity in Hepatic Cancer Cells and Normal Hepatocytes Leading to Enhancement of Its Therapeutic and Chemopreventive Potential
por: Narożna, Maria, et al.
Publicado: (2021)

The effect of resveratrol and its methylthio-derivatives on EGFR and Stat3 activation in human HaCaT and A431 cells
por: Cichocki, Michal, et al.
Publicado: (2014)

Cannabidiol and Its Combinations with Nonsteroidal Anti-Inflammatory Drugs Induce Apoptosis and Inhibit Activation of NF-κB Signaling in Vulvar Squamous Cell Carcinoma
por: Krajka-Kuźniak, Violetta, et al.
Publicado: (2022)

Effect of methoxy stilbenes—analogs of resveratrol—on the viability and induction of cell cycle arrest and apoptosis in human myeloid leukemia cells
por: Zielińska-Przyjemska, Małgorzata, et al.
Publicado: (2020)

COXIBs and 2,5-dimethylcelecoxib counteract the hyperactivated Wnt/β-catenin pathway and COX-2/PGE2/EP4 signaling in glioblastoma cells
por: Majchrzak-Celińska, Aleksandra, et al.
Publicado: (2021)

Etoricoxib-Cannabidiol Combo: Potential Role in Glioblastoma Treatment and Development of PLGA-Based Nanoparticles
por: Kuźmińska, Joanna, et al.
Publicado: (2023)

The Development of Magnolol-Loaded Intravenous Emulsion with Low Hepatotoxic Potential
por: Gostyńska, Aleksandra, et al.
Publicado: (2023)

Honokiol-Loaded Nanoemulsion for Glioblastoma Treatment: Statistical Optimization, Physicochemical Characterization, and an In Vitro Toxicity Assay
por: Gostyńska, Aleksandra, et al.
Publicado: (2023)

The Effect of 3′-Hydroxy-3,4,5,4′-Tetramethoxy -stilbene, the Metabolite of the Resveratrol Analogue DMU-212, on the Motility and Proliferation of Ovarian Cancer Cells
por: Nowicki, Andrzej, et al.
Publicado: (2020)

Roles of CNC Transcription Factors NRF1 and NRF2 in Cancer
por: Sekine, Hiroki, et al.
Publicado: (2021)

Role of NRF2 in Lung Cancer
por: Sánchez-Ortega, Miriam, et al.
Publicado: (2021)

Role of NRF2 in Ovarian Cancer
por: Tossetta, Giovanni, et al.
Publicado: (2022)

Dual roles and therapeutic potential of Keap1-Nrf2 pathway in pancreatic cancer: a systematic review
por: Qin, Jiang-Jiang, et al.
Publicado: (2019)

The ‘N-factors' in pancreatic cancer: functional relevance of NF-κB, NFAT and Nrf2 in pancreatic cancer
por: Arlt, A, et al.
Publicado: (2012)

HIF-1 and NRF2; Key Molecules for Malignant Phenotypes of Pancreatic Cancer
por: Hamada, Shin, et al.
Publicado: (2022)

The Role of Nrf2 Activity in Cancer Development and Progression
por: Zimta, Alina-Andreea, et al.
Publicado: (2019)

Role of NRF2 in Colorectal Cancer Prevention and Treatment
por: Li, Jiaxiang, et al.
Publicado: (2022)

Lichen Secondary Metabolites Inhibit the Wnt/β-Catenin Pathway in Glioblastoma Cells and Improve the Anticancer Effects of Temozolomide
por: Majchrzak-Celińska, Aleksandra, et al.
Publicado: (2022)

The Role of NRF2 in Mycobacterial Infection
por: Matsuyama, Masashi, et al.
Publicado: (2021)

Role of Nrf2 in bone metabolism
por: Sun, Yong-Xin, et al.
Publicado: (2015)

Roles of Nrf2 in Gastric Cancer: Targeting for Therapeutic Strategies
por: Farkhondeh, Tahereh, et al.
Publicado: (2021)

Cytoprotection “gone astray”: Nrf2 and its role in cancer
por: Geismann, Claudia, et al.
Publicado: (2014)

Neuroprotective Effects of Pomegranate Juice against Parkinson’s Disease and Presence of Ellagitannins-Derived Metabolite—Urolithin A—In the Brain
por: Kujawska, Małgorzata, et al.
Publicado: (2019)

Cellular senescence in skin‐related research: Targeted signaling pathways and naturally occurring therapeutic agents
por: Dańczak‐Pazdrowska, Aleksandra, et al.
Publicado: (2023)

Control of Oxidative Stress in Cancer Chemoresistance: Spotlight on Nrf2 Role
por: Barrera, Giuseppina, et al.
Publicado: (2021)

The Role of NRF2/KEAP1 Signaling Pathway in Cancer Metabolism
por: Song, Moon-Young, et al.
Publicado: (2021)

The emerging role of the Nrf2–Keap1 signaling pathway in cancer
por: Jaramillo, Melba C., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_t9gdt9u688ps3h3loifsem2og3