Cargando…
Zinc Supplementation Enhances the Pro-Death Function of UPR in Lymphoma Cells Exposed to Radiation
SIMPLE SUMMARY: It is of fundamental importance to find strategies able to reduce the minimum doses of anticancer treatments, such as radiations, and concomitantly maintain efficient killing of cancer cells. The interconnection between ER stress and DNA repair may represent a promising approach to o...
Autores principales: | Gonnella, Roberta, Guttieri, Luisa, Gilardini Montani, Maria Saveria, Santarelli, Roberta, Bassetti, Erica, D’Orazi, Gabriella, Cirone, Mara |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773084/ https://www.ncbi.nlm.nih.gov/pubmed/35053130 http://dx.doi.org/10.3390/biology11010132 |
Ejemplares similares
-
Role of UPR Sensor Activation in Cell Death–Survival Decision of Colon Cancer Cells Stressed by DPE Treatment
por: Benedetti, Rossella, et al.
Publicado: (2021) -
Apigenin, by activating p53 and inhibiting STAT3, modulates the balance between pro-apoptotic and pro-survival pathways to induce PEL cell death
por: Granato, Marisa, et al.
Publicado: (2017) -
IRE1 Alpha/XBP1 Axis Sustains Primary Effusion Lymphoma Cell Survival by Promoting Cytokine Release and STAT3 Activation
por: Gonnella, Roberta, et al.
Publicado: (2021) -
Lovastatin reduces PEL cell survival by phosphorylating ERK1/2 that blocks the autophagic flux and engages a cross‐talk with p53 to activate p21
por: Santarelli, Roberta, et al.
Publicado: (2021) -
Concomitant Inhibition of IRE1α/XBP1 Axis of UPR and PARP: A Promising Therapeutic Approach against c-Myc and Gammaherpesvirus-Driven B-Cell Lymphomas
por: Benedetti, Rossella, et al.
Publicado: (2022)