Human Lysyl Oxidase Over-Expression Enhances Baseline Cardiac Oxidative Stress but Does Not Aggravate ROS Generation or Infarct Size Following Myocardial Ischemia-Reperfusion

Lysyl oxidase (LOX) is an enzyme critically involved in collagen maturation, whose activity releases H(2)O(2) as a by-product. Previous studies demonstrated that LOX over-expression enhances reactive oxygen species (ROS) production and exacerbates cardiac remodeling induced by pressure overload. How...

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Detalles Bibliográficos
Autores principales: Valls-Lacalle, Laura, Puertas-Umbert, Lídia, Varona, Saray, Martínez-González, José, Rodríguez, Cristina, Rodríguez-Sinovas, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773108/
https://www.ncbi.nlm.nih.gov/pubmed/35052579
http://dx.doi.org/10.3390/antiox11010075

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