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Large-Scale Functional Genomics Screen to Identify Modulators of Human β-Cell Insulin Secretion

Type 2 diabetes (T2D) is a chronic metabolic disorder affecting almost half a billion people worldwide. Impaired function of pancreatic β-cells is both a hallmark of T2D and an underlying factor in the pathophysiology of the disease. Understanding the cellular mechanisms regulating appropriate insul...

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Detalles Bibliográficos
Autores principales: Szczerbinska, Iwona, Tessitore, Annamaria, Hansson, Lena Kristina, Agrawal, Asmita, Ragel Lopez, Alejandro, Helenius, Marianne, Malinowski, Andrzej R., Gilboa, Barak, Ruby, Maxwell A., Gupta, Ramneek, Ämmälä, Carina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773179/
https://www.ncbi.nlm.nih.gov/pubmed/35052782
http://dx.doi.org/10.3390/biomedicines10010103