Cargando…

TERT Promoter Revertant Mutation Inhibits Melanoma Growth through Intrinsic Apoptosis

SIMPLE SUMMARY: TERT -146 C>T frequently occurs in many cancer cells. Research targeting the telomerase reverse transcriptase (TERT) promoter contributes to a better understanding of cancer development and treatment. Many conventional cancer treatments aim to develop new drugs targeting TERT. Her...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yanbing, Chen, Yiwu, Li, Chang, Xiao, Zhiwei, Yuan, Hongming, Zhang, Yuanzhu, Pang, Daxin, Tang, Xiaochun, Li, Mengjing, Ouyang, Hongsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773187/ https://www.ncbi.nlm.nih.gov/pubmed/35053139 http://dx.doi.org/10.3390/biology11010141

Ejemplares similares

Correction: Wang et al. TERT Promoter Revertant Mutation Inhibits Melanoma Growth through Intrinsic Apoptosis. Biology 2022, 11, 141
por: Wang, Yanbing, et al.
Publicado: (2022)

Large-Scale CRISPR Screen of LDLR Pathogenic Variants
por: Li, Mengjing, et al.
Publicado: (2023)

HMEJ-mediated site-specific integration of a myostatin inhibitor increases skeletal muscle mass in porcine
por: Li, Mengjing, et al.
Publicado: (2021)

HMEJ-mediated site-specific integration of a myostatin inhibitor increases skeletal muscle mass in porcine
por: Li, Mengjing, et al.
Publicado: (2023)

CRISPR/Cas9-Mediated Specific Integration of Fat-1 and IGF-1 at the pRosa26 Locus
por: You, Wenni, et al.
Publicado: (2021)

Efficient Generation of Orthologous Point Mutations in Pigs via CRISPR-assisted ssODN-mediated Homology-directed Repair
por: Wang, Kankan, et al.
Publicado: (2016)

Porcine Epidemic Diarrhea Virus: An Updated Overview of Virus Epidemiology, Virulence Variation Patterns and Virus–Host Interactions
por: Zhang, Yuanzhu, et al.
Publicado: (2022)

Transmissible Gastroenteritis Virus: An Update Review and Perspective
por: Chen, Yiwu, et al.
Publicado: (2023)

Current Status of Genetically Modified Pigs That Are Resistant to Virus Infection
por: Yuan, Hongming, et al.
Publicado: (2022)

Optimization of a CRISPR/Cas9-mediated Knock-in Strategy at the Porcine Rosa26 Locus in Porcine Foetal Fibroblasts
por: Xie, Zicong, et al.
Publicado: (2017)

Site-Specific Fat-1 Knock-In Enables Significant Decrease of n-6PUFAs/n-3PUFAs Ratio in Pigs
por: Li, Mengjing, et al.
Publicado: (2018)

Efficient Generation of Myostatin Mutations in Pigs Using the CRISPR/Cas9 System
por: Wang, Kankan, et al.
Publicado: (2015)

CRISPR/Cas9-Mediated Hitchhike Expression of Functional shRNAs at the Porcine miR-17-92 Cluster
por: Lu, Chao, et al.
Publicado: (2019)

TERT promoter mutations in melanoma survival
por: Nagore, Eduardo, et al.
Publicado: (2019)

TERT Promoter Mutations and Telomerase in Melanoma
por: Guo, Yuchen, et al.
Publicado: (2022)

Pathological alterations in the gastrointestinal tract of a porcine model of DMD
por: Zou, Xiaodong, et al.
Publicado: (2021)

Advance of genetically modified pigs in xeno-transplantation
por: Deng, Jiacheng, et al.
Publicado: (2022)

TERT promoter mutations in melanoma render TERT expression dependent on MAPK pathway activation
por: Vallarelli, Andrelou F., et al.
Publicado: (2016)

Germline TERT promoter mutations are rare in familial melanoma
por: Harland, Mark, et al.
Publicado: (2015)

Clostridium butyricum and Bifidobacterium pseudolongum Attenuate the Development of Cardiac Fibrosis in Mice
por: Wang, Jiaqi, et al.
Publicado: (2022)

Preparation of a new type 2 diabetic miniature pig model via the CRISPR/Cas9 system
por: Zou, Xiaodong, et al.
Publicado: (2019)

Genetically modified pigs are protected from classical swine fever virus
por: Xie, Zicong, et al.
Publicado: (2018)

TERT Promoter Mutations are Associated with Visceral Spreading in Melanoma of the Trunk
por: Osella-Abate, Simona, et al.
Publicado: (2019)

Germ cell‐specific expression of Cre recombinase using the VASA promoter in the pig
por: Song, Yuning, et al.
Publicado: (2015)

N-3 polyunsaturated fatty acids attenuates triglyceride and inflammatory factors level in hfat-1 transgenic pigs
por: Liu, Xingxing, et al.
Publicado: (2016)

Cholesterol Biosynthesis Modulates CSFV Replication
por: Zou, Xiaodong, et al.
Publicado: (2022)

MYBPC3 deficiency in cardiac fibroblasts drives their activation and contributes to fibrosis
por: Zou, Xiaodong, et al.
Publicado: (2022)

Will It Revert to Pageantry and Burlesque?
Publicado: (1920)

ETNK1 mutations induce a mutator phenotype that can be reverted with phosphoethanolamine
por: Fontana, Diletta, et al.
Publicado: (2020)

Male patients with TERT mutation may be more likely to benefit from immunotherapy, especially for melanoma
por: Li, Jia, et al.
Publicado: (2020)

TERT promoter mutations in ocular melanoma distinguish between conjunctival and uveal tumours
por: Griewank, K G, et al.
Publicado: (2013)

Molecular Genetics of Conjunctival Melanoma and Prognostic Value of TERT Promoter Mutation Analysis
por: van Poppelen, Natasha M., et al.
Publicado: (2021)

Apolipoprotein CIII regulates lipoprotein-associated phospholipase A(2) expression via the MAPK and NFκB pathways
por: Han, Xiaolei, et al.
Publicado: (2015)

Lactate facilitates classical swine fever virus replication by enhancing cholesterol biosynthesis
por: Zou, Xiaodong, et al.
Publicado: (2022)

Revertant mosaicism for family mutations is not observed in BRCA1/2 phenocopies
por: Azzollini, Jacopo, et al.
Publicado: (2017)

CRISPR/Cas9-mediated knockin of human factor IX into swine factor IX locus effectively alleviates bleeding in hemophilia B pigs
por: Chen, Jiahuan, et al.
Publicado: (2020)

Efficiency of porcine somatic cell nuclear transfer – a retrospective study of factors related to embryo recipient and embryos transferred
por: Huang, Yongye, et al.
Publicado: (2013)

TERT promoter mutations and monoallelic activation of TERT in cancer
por: Huang, F W, et al.
Publicado: (2015)

Revertant Mosaicism in Epidermolysis Bullosa
por: Meyer-Mueller, Cameron, et al.
Publicado: (2022)

A "late-but-fitter revertant cell" explains the high frequency of revertant mosaicism in epidermolysis bullosa
por: van den Akker, Peter C., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ijiufbkhisms13ucvdosi6mvcr