Cargando…

Targeting the Ghrelin Receptor as a Novel Therapeutic Option for Epilepsy

Epilepsy is a neurological disease affecting more than 50 million individuals worldwide. Notwithstanding the availability of a broad array of antiseizure drugs (ASDs), 30% of patients suffer from pharmacoresistant epilepsy. This highlights the urgent need for novel therapeutic options, preferably wi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Buckinx, An, De Bundel, Dimitri, Kooijman, Ron, Smolders, Ilse
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773216/ https://www.ncbi.nlm.nih.gov/pubmed/35052733 http://dx.doi.org/10.3390/biomedicines10010053

Ejemplares similares

Differential Effects of a Full and Biased Ghrelin Receptor Agonist in a Mouse Kindling Model
por: Buckinx, An, et al.
Publicado: (2019)

Psychedelic-Induced Serotonin 2A Receptor Downregulation Does Not Predict Swim Stress Coping in Mice
por: Pędzich, Błażej D., et al.
Publicado: (2022)

Exploring Refinement Strategies for Single Housing of Male C57BL/6JRj Mice: Effect of Cage Divider on Stress-Related Behavior and Hypothalamic-Pituitary-Adrenal-Axis Activity
por: Buckinx, An, et al.
Publicado: (2021)

Preclinical evidence of ghrelin as a therapeutic target in epilepsy
por: Ge, Tongtong, et al.
Publicado: (2017)

Caloric Restriction Protects against Lactacystin-Induced Degeneration of Dopamine Neurons Independent of the Ghrelin Receptor
por: Coppens, Jessica, et al.
Publicado: (2017)

Current Approaches to Monitor Macromolecules Directly from the Cerebral Interstitial Fluid
por: Custers, Marie-Laure, et al.
Publicado: (2022)

The Good, the Bad and the Unknown Aspects of Ghrelin in Stress Coping and Stress-Related Psychiatric Disorders
por: Fritz, Eva Maria, et al.
Publicado: (2020)

Ghrelin receptor agonist MK0677 and overnight fasting do not rescue deficient fear extinction in 129S1/SvImJ mice
por: Fritz, Eva Maria, et al.
Publicado: (2023)

Critical Evaluation of Acetylcholine Determination in Rat Brain Microdialysates using Ion-Pair Liquid Chromatography with Amperometric Detection
por: De Bundel, Dimitri, et al.
Publicado: (2008)

Astrocytic Connexin43 Channels as Candidate Targets in Epilepsy Treatment
por: Walrave, Laura, et al.
Publicado: (2020)

Therapeutic Potential of Targeting the Ghrelin Pathway
por: Colldén, Gustav, et al.
Publicado: (2017)

Inhibition of Connexin43 Hemichannels Impairs Spatial Short-Term Memory without Affecting Spatial Working Memory
por: Walrave, Laura, et al.
Publicado: (2016)

Therapeutic Options for Childhood Absence Epilepsy
por: Rinaldi, Victoria Elisa, et al.
Publicado: (2021)

Montelukast: The New Therapeutic Option for the Treatment of Epilepsy
por: Tesfaye, Bekalu Amare, et al.
Publicado: (2021)

Epilepsy: Novel therapeutic targets
por: Anovadiya, Ashish P., et al.
Publicado: (2012)

The CB(2) Receptor as a Novel Therapeutic Target for Epilepsy Treatment
por: Ji, Xiaoyu, et al.
Publicado: (2021)

Monoaminergic Mechanisms in Epilepsy May Offer Innovative Therapeutic Opportunity for Monoaminergic Multi-Target Drugs
por: Svob Strac, Dubravka, et al.
Publicado: (2016)

Side-by-side comparison of the effects of Gq- and Gi-DREADD-mediated astrocyte modulation on intracellular calcium dynamics and synaptic plasticity in the hippocampal CA1
por: Van Den Herrewegen, Yana, et al.
Publicado: (2021)

Prospective Evaluation of Ghrelin and Des-Acyl Ghrelin Plasma Levels in Children with Newly Diagnosed Epilepsy: Evidence for Reduced Ghrelin-to-Des-Acyl Ghrelin Ratio in Generalized Epilepsies
por: Costa, Anna-Maria, et al.
Publicado: (2022)

Higher susceptibility to 6 Hz corneal kindling and lower responsiveness to antiseizure drugs in mouse models of Alzheimer's disease
por: Vande Vyver, Maxime, et al.
Publicado: (2022)

The intracerebral injection of Aβ(1-42) oligomers does not invariably alter seizure susceptibility in mice
por: Vande Vyver, Maxime, et al.
Publicado: (2023)

Are vesicular neurotransmitter transporters potential treatment targets for temporal lobe epilepsy?
por: Van Liefferinge, Joeri, et al.
Publicado: (2013)

Network science for the identification of novel therapeutic targets in epilepsy
por: Scott, Rod C.
Publicado: (2016)

Serotonin receptors in epilepsy: Novel treatment targets?
por: Sourbron, Jo, et al.
Publicado: (2022)

Ghrelin and ghrelin receptor modulation of psychostimulant action
por: Wellman, Paul J., et al.
Publicado: (2013)

Novel astrocyte targets: New Avenues for the Therapeutic Treatment of Epilepsy
por: Crunelli, Vincenzo, et al.
Publicado: (2015)

Ghrelin, MicroRNAs, and Critical Limb Ischemia: Hungering for a Novel Treatment Option
por: Neale, Joshua P. H., et al.
Publicado: (2017)

Targeting Necroptosis: A Novel Therapeutic Option for Retinal Degenerative Diseases
por: Zhang, Qi, et al.
Publicado: (2023)

Capromorelin: a ghrelin receptor agonist and novel therapy for stimulation of appetite in dogs
por: Rhodes, Linda, et al.
Publicado: (2017)

From Belly to Brain: Targeting the Ghrelin Receptor in Appetite and Food Intake Regulation
por: Howick, Ken, et al.
Publicado: (2017)

The Role of Ghrelin and Ghrelin Signaling in Aging
por: Amitani, Marie, et al.
Publicado: (2017)

Editorial: Complex Scenarios of Drug-Resistant Epilepsies: Diagnostic Challenges and Novel Therapeutic Options
por: Didato, Giuseppe, et al.
Publicado: (2022)

Ex Vivo Feedback Control of Neurotransmission Using a Photocaged Adenosine A1 Receptor Agonist
por: Craey, Erine, et al.
Publicado: (2022)

Therapeutic Success of the Ketogenic Diet as a Treatment Option for Epilepsy: a Meta-analysis
por: Li, Hai-feng, et al.
Publicado: (2013)

Neurokinin-1 Receptor Antagonists as a Potential Novel Therapeutic Option for Osteosarcoma Patients
por: Robinson, Prema, et al.
Publicado: (2023)

Designer receptor technology for the treatment of epilepsy
por: Lieb, Andreas, et al.
Publicado: (2019)

Targeting ferroptosis as novel therapeutic approaches for epilepsy
por: Jin, Yuzi, et al.
Publicado: (2023)

Effect of Ghrelin on Glucose-Insulin Homeostasis: Therapeutic Implications
por: Sangiao-Alvarellos, Susana, et al.
Publicado: (2010)

Targeted inhibition of tumor-derived exosomes as a novel therapeutic option for cancer
por: Li, Ye, et al.
Publicado: (2022)

Is there an effect of ghrelin/ghrelin analogs on cancer? A systematic review
por: Sever, Sakine, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_5qbatf2bk4h1p2qk2j2djosk11