Repositioning Fenofibrate to Reactivate p53 and Reprogram the Tumor-Immune Microenvironment in HPV+ Head and Neck Squamous Cell Carcinoma

SIMPLE SUMMARY: A critical need for optimal management of human papillomavirus-associated head and neck squamous cell carcinoma (HPV+ HNSCC) patients is the development of therapeutic strategies to exploit the inherent vulnerabilities of this unique disease. We identified fenofibrate, an FDA-approve...

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Detalles Bibliográficos
Autores principales: O’Neill, W. Quinn, Xie, Xiujie, Gui, Shanying, Yu, Heping, Davenport, Jacqueline, Cartwright, Thomas, Storl-Desmond, Marta, Ryu, Esther, Chan, Ernest R., Cao, Shufen, Fu, Pingfu, Teknos, Theodoros N., Pan, Quintin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773501/
https://www.ncbi.nlm.nih.gov/pubmed/35053444
http://dx.doi.org/10.3390/cancers14020282

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