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Caregiver Burden and Quality of Life in Late Stage Parkinson’s Disease

Parkinson’s disease (PD) is a chronic, progressive, neurodegenerative disease involving both motor and non-motor symptoms (NMS). In the late stage of the disease, Hoehn and Yahr (HY) stages IV-V, the symptomatology is often severe and patients become increasingly dependent on help in their daily lif...

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Autores principales: Rosqvist, Kristina, Schrag, Anette, Odin, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773513/
https://www.ncbi.nlm.nih.gov/pubmed/35053854
http://dx.doi.org/10.3390/brainsci12010111
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author Rosqvist, Kristina
Schrag, Anette
Odin, Per
author_facet Rosqvist, Kristina
Schrag, Anette
Odin, Per
author_sort Rosqvist, Kristina
collection PubMed
description Parkinson’s disease (PD) is a chronic, progressive, neurodegenerative disease involving both motor and non-motor symptoms (NMS). In the late stage of the disease, Hoehn and Yahr (HY) stages IV-V, the symptomatology is often severe and patients become increasingly dependent on help in their daily life, resulting in an increased burden for the informal caregivers. To assess the implications of the caregiver burden, caregiver quality of life (QoL) was assessed in 74 informal caregivers to patients in late stage PD, by the Alzheimer’s Patient Partners Life Impact Questionnaire (APPLIQue), which has been found useful also in PD. The majority of caregivers were the spouse/partner. Individual items provided information on which aspects of caregiver burden were the most common, i.e., items: “feel guilty if not there” (71% affirmed), “situation wears me down” (65% affirmed) and “always on my mind” (61% affirmed). In simple linear regression analyses, female patient gender (p = 0.007), better cognition (p = 0.004), lower NMS burden (p = 0.012) and not being the partner (p = 0.022) were associated with better caregiver QoL. Multivariable linear regression analyses identified better cognition (p = 0.004) and female patient gender (p = 0.035) as independently associated with better informal caregiver QoL. Identifying and treating NMS as well as recognizing and alleviating caregiver burden seem essential to enhance QoL for both patients and caregivers in late stage PD.
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spelling pubmed-87735132022-01-21 Caregiver Burden and Quality of Life in Late Stage Parkinson’s Disease Rosqvist, Kristina Schrag, Anette Odin, Per Brain Sci Article Parkinson’s disease (PD) is a chronic, progressive, neurodegenerative disease involving both motor and non-motor symptoms (NMS). In the late stage of the disease, Hoehn and Yahr (HY) stages IV-V, the symptomatology is often severe and patients become increasingly dependent on help in their daily life, resulting in an increased burden for the informal caregivers. To assess the implications of the caregiver burden, caregiver quality of life (QoL) was assessed in 74 informal caregivers to patients in late stage PD, by the Alzheimer’s Patient Partners Life Impact Questionnaire (APPLIQue), which has been found useful also in PD. The majority of caregivers were the spouse/partner. Individual items provided information on which aspects of caregiver burden were the most common, i.e., items: “feel guilty if not there” (71% affirmed), “situation wears me down” (65% affirmed) and “always on my mind” (61% affirmed). In simple linear regression analyses, female patient gender (p = 0.007), better cognition (p = 0.004), lower NMS burden (p = 0.012) and not being the partner (p = 0.022) were associated with better caregiver QoL. Multivariable linear regression analyses identified better cognition (p = 0.004) and female patient gender (p = 0.035) as independently associated with better informal caregiver QoL. Identifying and treating NMS as well as recognizing and alleviating caregiver burden seem essential to enhance QoL for both patients and caregivers in late stage PD. MDPI 2022-01-14 /pmc/articles/PMC8773513/ /pubmed/35053854 http://dx.doi.org/10.3390/brainsci12010111 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Rosqvist, Kristina
Schrag, Anette
Odin, Per
Caregiver Burden and Quality of Life in Late Stage Parkinson’s Disease
title Caregiver Burden and Quality of Life in Late Stage Parkinson’s Disease
title_full Caregiver Burden and Quality of Life in Late Stage Parkinson’s Disease
title_fullStr Caregiver Burden and Quality of Life in Late Stage Parkinson’s Disease
title_full_unstemmed Caregiver Burden and Quality of Life in Late Stage Parkinson’s Disease
title_short Caregiver Burden and Quality of Life in Late Stage Parkinson’s Disease
title_sort caregiver burden and quality of life in late stage parkinson’s disease
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773513/
https://www.ncbi.nlm.nih.gov/pubmed/35053854
http://dx.doi.org/10.3390/brainsci12010111
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