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No Protective Effects of Hair Cells or Supporting Cells in Ototoxically Deafened Guinea Pigs upon Administration of BDNF

We investigated whether treatment with brain-derived neurotrophic factor (BDNF), which is known to protect spiral ganglion cells (SGCs), could also protect hair cells (HCs) and supporting cells (SCs) in the organ of Corti of a guinea pig model of sensorineural hearing loss. Hearing loss was induced...

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Detalles Bibliográficos
Autores principales: Tisi, Annamaria, Rovers, Jochebed, Vink, Henk A., Ramekers, Dyan, Maccarone, Rita, Versnel, Huib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773526/
https://www.ncbi.nlm.nih.gov/pubmed/35053747
http://dx.doi.org/10.3390/brainsci12010002