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Changes in Pronoun Use a Decade before Clinical Diagnosis of Alzheimer’s Dementia—Linguistic Contexts Suggest Problems in Perspective-Taking

The use of pronouns has been shown to change pathologically in the early phases of Alzheimer’s Dementia (AD). So far, the findings have been of a quantitative nature. Little is known, however, about the developmental path of the change, its onset, the domains in which it initially occurs, and if and...

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Autores principales: Bittner, Dagmar, Frankenberg, Claudia, Schröder, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773561/
https://www.ncbi.nlm.nih.gov/pubmed/35053864
http://dx.doi.org/10.3390/brainsci12010121
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author Bittner, Dagmar
Frankenberg, Claudia
Schröder, Johannes
author_facet Bittner, Dagmar
Frankenberg, Claudia
Schröder, Johannes
author_sort Bittner, Dagmar
collection PubMed
description The use of pronouns has been shown to change pathologically in the early phases of Alzheimer’s Dementia (AD). So far, the findings have been of a quantitative nature. Little is known, however, about the developmental path of the change, its onset, the domains in which it initially occurs, and if and how it spreads to other linguistic domains. The present study investigates pronoun use in six speakers of German a decade before they were clinically diagnosed with AD (LAD) and six biographically matched healthy controls (CTR). The data originate from monologic spoken language elicited by semi-spontaneous biographical interviews. Investigation of nine pronoun types revealed group differences in the use of three pronoun types: D-pronouns—a specific pronoun type of German for reference to persons and objects; the impersonal pronoun man ‘one’, and the propositional pronoun das ‘this/that’. Investigation of the linguistic contexts in which these three pronoun types were used revealed a correlation with declines in elaborative and evaluative information; that is, information the hearer would benefit from in creating an informed model of the discourse. We, therefore, hypothesize that the early changes in language use due to AD point to problems in perspective-taking, specifically in taking the hearer’s perspective.
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spelling pubmed-87735612022-01-21 Changes in Pronoun Use a Decade before Clinical Diagnosis of Alzheimer’s Dementia—Linguistic Contexts Suggest Problems in Perspective-Taking Bittner, Dagmar Frankenberg, Claudia Schröder, Johannes Brain Sci Article The use of pronouns has been shown to change pathologically in the early phases of Alzheimer’s Dementia (AD). So far, the findings have been of a quantitative nature. Little is known, however, about the developmental path of the change, its onset, the domains in which it initially occurs, and if and how it spreads to other linguistic domains. The present study investigates pronoun use in six speakers of German a decade before they were clinically diagnosed with AD (LAD) and six biographically matched healthy controls (CTR). The data originate from monologic spoken language elicited by semi-spontaneous biographical interviews. Investigation of nine pronoun types revealed group differences in the use of three pronoun types: D-pronouns—a specific pronoun type of German for reference to persons and objects; the impersonal pronoun man ‘one’, and the propositional pronoun das ‘this/that’. Investigation of the linguistic contexts in which these three pronoun types were used revealed a correlation with declines in elaborative and evaluative information; that is, information the hearer would benefit from in creating an informed model of the discourse. We, therefore, hypothesize that the early changes in language use due to AD point to problems in perspective-taking, specifically in taking the hearer’s perspective. MDPI 2022-01-17 /pmc/articles/PMC8773561/ /pubmed/35053864 http://dx.doi.org/10.3390/brainsci12010121 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bittner, Dagmar
Frankenberg, Claudia
Schröder, Johannes
Changes in Pronoun Use a Decade before Clinical Diagnosis of Alzheimer’s Dementia—Linguistic Contexts Suggest Problems in Perspective-Taking
title Changes in Pronoun Use a Decade before Clinical Diagnosis of Alzheimer’s Dementia—Linguistic Contexts Suggest Problems in Perspective-Taking
title_full Changes in Pronoun Use a Decade before Clinical Diagnosis of Alzheimer’s Dementia—Linguistic Contexts Suggest Problems in Perspective-Taking
title_fullStr Changes in Pronoun Use a Decade before Clinical Diagnosis of Alzheimer’s Dementia—Linguistic Contexts Suggest Problems in Perspective-Taking
title_full_unstemmed Changes in Pronoun Use a Decade before Clinical Diagnosis of Alzheimer’s Dementia—Linguistic Contexts Suggest Problems in Perspective-Taking
title_short Changes in Pronoun Use a Decade before Clinical Diagnosis of Alzheimer’s Dementia—Linguistic Contexts Suggest Problems in Perspective-Taking
title_sort changes in pronoun use a decade before clinical diagnosis of alzheimer’s dementia—linguistic contexts suggest problems in perspective-taking
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773561/
https://www.ncbi.nlm.nih.gov/pubmed/35053864
http://dx.doi.org/10.3390/brainsci12010121
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