HELLS Is Negatively Regulated by Wild-Type P53 in Liver Cancer by a Mechanism Involving P21 and FOXM1

SIMPLE SUMMARY: The tumor suppressor protein P53 is a major player in preventing liver cancer development and progression. In this study we could show that P53 negatively regulates the expression of Helicase, lymphoid specific (HELLS), previously described as an important pro-tumorigenic epigenetic...

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Detalles Bibliográficos
Autores principales: Schuller, Stefanie, Sieker, Jan, Riemenschneider, Philip, Köhler, Bianca, Drucker, Elisabeth, Weiler, Sofia M. E., Dauch, Daniel, Sticht, Carsten, Goeppert, Benjamin, Roessler, Stephanie, Ribback, Silvia, Breuhahn, Kai, Fend, Falko, Dombrowski, Frank, Singer, Kerstin, Singer, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773711/
https://www.ncbi.nlm.nih.gov/pubmed/35053620
http://dx.doi.org/10.3390/cancers14020459

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