Cargando…

Adipose Triglyceride Lipase in Hepatic Physiology and Pathophysiology

The liver is extremely active in oxidizing triglycerides (TG) for energy production. An imbalance between TG synthesis and hydrolysis leads to metabolic disorders in the liver, including excessive lipid accumulation, oxidative stress, and ultimately liver damage. Adipose triglyceride lipase (ATGL) i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Tianjiao, Guo, Wei, Zhou, Zhanxiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773762/ https://www.ncbi.nlm.nih.gov/pubmed/35053204 http://dx.doi.org/10.3390/biom12010057

Ejemplares similares

Of mice and men: The physiological role of adipose triglyceride lipase (ATGL)()
por: Schreiber, Renate, et al.
Publicado: (2019)

Adipose triglyceride lipase is involved in the mobilization of triglyceride and retinoid stores of hepatic stellate cells
por: Taschler, Ulrike, et al.
Publicado: (2015)

Endothelial dysfunction in adipose triglyceride lipase deficiency
por: Schrammel, Astrid, et al.
Publicado: (2014)

Adipose triglyceride lipase: the first transacylase for FAHFAs
por: Wang, Juan, et al.
Publicado: (2023)

Pleiotropic regulation of mitochondrial function by adipose triglyceride lipase-mediated lipolysis()
por: Kratky, Dagmar, et al.
Publicado: (2014)

The Role of Adipose Triglyceride Lipase and Cytosolic Lipolysis in Cardiac Function and Heart Failure
por: Kintscher, Ulrich, et al.
Publicado: (2020)

Endothelial dysfunction in adipose triglyceride lipase deficiency: role of perivascular adipose tissue
por: Mussbacher, Marion, et al.
Publicado: (2013)

Efficient Phagocytosis Requires Triacylglycerol Hydrolysis by Adipose Triglyceride Lipase
por: Chandak, Prakash G., et al.
Publicado: (2010)

Development of small molecule inhibitors targeting adipose triglyceride lipase
por: Mayer, Nicole, et al.
Publicado: (2013)

The role of adipose triglyceride lipase in lipid and glucose homeostasis: lessons from transgenic mice
por: Trites, Michael J., et al.
Publicado: (2019)

Role of perivascular adipose tissue in endothelial dysfunction of adipose triglyceride lipase-deficient mice
por: Pail, Karoline, et al.
Publicado: (2012)

LncRNA SRA promotes hepatic steatosis through repressing the expression of adipose triglyceride lipase (ATGL)
por: Chen, Gang, et al.
Publicado: (2016)

Adipose triglyceride lipase–mediated lipid catabolism is essential for bronchiolar regeneration
por: Kanti, Manu Manjunath, et al.
Publicado: (2022)

Deficiency of Adipose Triglyceride Lipase Induces Metabolic Syndrome and Cardiomyopathy in Zebrafish
por: Lai, Hsin-Hung, et al.
Publicado: (2022)

Adipose Triglyceride Lipase and Hormone-Sensitive Lipase Are Involved in Fat Loss in JunB-Deficient Mice
por: Pinent, Montserrat, et al.
Publicado: (2011)

Hormone-sensitive lipase protects adipose triglyceride lipase-deficient mice from lethal lipotoxic cardiomyopathy
por: Yamada, Mika, et al.
Publicado: (2022)

The role of triglyceride lipases in cancer associated cachexia
por: Das, Suman K., et al.
Publicado: (2013)

Physiological and metabolomic consequences of reduced expression of the Drosophila brummer triglyceride Lipase
por: Nazario-Yepiz, Nestor O., et al.
Publicado: (2021)

Data on hepatic lipolysis, adipose triglyceride lipase, and hormone-sensitive lipase in fasted and non-fasted C57BL/6J female mice
por: Marvyn, Phillip M., et al.
Publicado: (2016)

Genetic Deficiency of Adipose Triglyceride Lipase Is Associated With a Novel Type of Podocytopathy
por: Nagasawa, Yasuyuki, et al.
Publicado: (2021)

Adipose triglyceride lipase activity is inhibited by long-chain acyl-coenzyme A
por: Nagy, Harald M., et al.
Publicado: (2014)

Nitric oxide signaling in adipose triglyceride lipase-deficient microvascular endothelial cells
por: Mussbacher, Marion, et al.
Publicado: (2012)

Hypoxia-inducible lipid droplet-associated protein inhibits adipose triglyceride lipase
por: Padmanabha Das, Krishna M., et al.
Publicado: (2018)

Optimized expression and purification of adipose triglyceride lipase improved hydrolytic and transacylation activities in vitro
por: Kulminskaya, Natalia, et al.
Publicado: (2021)

Pigment Epithelium–Derived Factor Regulates Lipid Metabolism via Adipose Triglyceride Lipase
por: Borg, Melissa L., et al.
Publicado: (2011)

Cardiac dysfunction in adipose triglyceride lipase deficiency: treatment with a PPARα agonist
por: Wölkart, G, et al.
Publicado: (2012)

Role of the ubiquitin–proteasome system in cardiac dysfunction of adipose triglyceride lipase-deficient mice
por: Mussbacher, Marion, et al.
Publicado: (2014)

Deletion of CGI-58 or adipose triglyceride lipase differently affects macrophage function and atherosclerosis
por: Goeritzer, Madeleine, et al.
Publicado: (2014)

Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia
por: Al-Zoughbi, Wael, et al.
Publicado: (2016)

Adipose triglyceride lipase promotes the proliferation of colorectal cancer cells via enhancing the lipolytic pathway
por: Yin, Haofan, et al.
Publicado: (2021)

Triglyceride-Tethered Membrane Lipase Sensor
por: Lankage, Upeksha Mirissa, et al.
Publicado: (2023)

Myocardial Adipose Triglyceride Lipase Overexpression Protects Diabetic Mice From the Development of Lipotoxic Cardiomyopathy
por: Pulinilkunnil, Thomas, et al.
Publicado: (2013)

Structure–activity studies in the development of a hydrazone based inhibitor of adipose-triglyceride lipase (ATGL)
por: Mayer, Nicole, et al.
Publicado: (2015)

Blocking Lipid Uptake Pathways Does not Prevent Toxicity in Adipose Triglyceride Lipase (ATGL) Deficiency
por: Oluwadare, Jide, et al.
Publicado: (2022)

Myocardial Adipose Triglyceride Lipase Overexpression Protects against Burn-Induced Cardiac Lipid Accumulation and Injury
por: Li, Lingfei, et al.
Publicado: (2019)

Alcohol predisposes obese mice to acute pancreatitis via adipose triglyceride lipase-dependent visceral adipocyte lipolysis
por: Yang, Xinmin, et al.
Publicado: (2023)

Adipose triglyceride lipase (ATGL) expression in human skeletal muscle is type I (oxidative) fiber specific
por: Jocken, Johan W. E., et al.
Publicado: (2008)

Adipose triglyceride lipase is a TG hydrolase of the small intestine and regulates intestinal PPARα signaling
por: Obrowsky, Sascha, et al.
Publicado: (2013)

Adipose triglyceride lipase acts on neutrophil lipid droplets to regulate substrate availability for lipid mediator synthesis
por: Schlager, Stefanie, et al.
Publicado: (2015)

Berberine increases adipose triglyceride lipase in 3T3-L1 adipocytes through the AMPK pathway
por: Jiang, Dongqing, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_rcfhb3288npp4qaclleiqnnnlh