Phosphorylation-Induced Ubiquitination and Degradation of PXR through CDK2-TRIM21 Axis

Pregnane X receptor (PXR) is a member of the nuclear receptor superfamily that is activated by a variety of endogenous metabolites or xenobiotics. Its downstream target genes are involved in metabolism, inflammation and processes closely related to cancer. However, the stability regulation of PXR pr...

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Detalles Bibliográficos
Autores principales: Qin, Mengyao, Xin, Yu, Bian, Yong, Yang, Xuan, Xi, Tao, Xiong, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773821/
https://www.ncbi.nlm.nih.gov/pubmed/35053380
http://dx.doi.org/10.3390/cells11020264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773821/
https://www.ncbi.nlm.nih.gov/pubmed/35053380
http://dx.doi.org/10.3390/cells11020264

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