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Implant Survival, Clinical Outcome and Complications of Megaprosthetic Reconstructions Following Sarcoma Resection
SIMPLE SUMMARY: Malignant bone and soft tissue tumors are usually surgically removed with an envelope of healthy tissue as a barrier. If located in the long bones of the upper and lower extremity, this approach leads to a large bone defect commonly affecting a joint. One way to rebuild the bone defe...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773828/ https://www.ncbi.nlm.nih.gov/pubmed/35053514 http://dx.doi.org/10.3390/cancers14020351 |
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author | Theil, Christoph Schwarze, Jan Gosheger, Georg Moellenbeck, Burkhard Schneider, Kristian Nikolaus Deventer, Niklas Klingebiel, Sebastian Grammatopoulos, George Boettner, Friedrich Schmidt-Braekling, Tom |
author_facet | Theil, Christoph Schwarze, Jan Gosheger, Georg Moellenbeck, Burkhard Schneider, Kristian Nikolaus Deventer, Niklas Klingebiel, Sebastian Grammatopoulos, George Boettner, Friedrich Schmidt-Braekling, Tom |
author_sort | Theil, Christoph |
collection | PubMed |
description | SIMPLE SUMMARY: Malignant bone and soft tissue tumors are usually surgically removed with an envelope of healthy tissue as a barrier. If located in the long bones of the upper and lower extremity, this approach leads to a large bone defect commonly affecting a joint. One way to rebuild the bone defect and the neighboring joint is the use of a megaprosthesis that is anchored in the remaining bone comparable to a conventional joint replacement. In general this approach is popular as it provides early stability and allows the affected patient to begin rehabilitation early on. However, complications leading to long-term unplanned reoperation are common. This article provides an overview of current implant survival, types of complication and long-term outcomes of megaprostheses used following tumor resection. ABSTRACT: Megaprosthetic reconstruction of segmental bone defects following sarcoma resection is a frequently chosen surgical approach in orthopedic oncology. While the use of megaprostheses has gained popularity over the last decades and such implants are increasingly used for metastatic reconstructions and in non-tumor cases, there still is a high risk of long-term complications leading to revision surgery. This article investigates current implant survivorship, frequency and types of complications as well as functional outcomes of upper and lower limb megaprosthetic reconstructions. |
format | Online Article Text |
id | pubmed-8773828 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87738282022-01-21 Implant Survival, Clinical Outcome and Complications of Megaprosthetic Reconstructions Following Sarcoma Resection Theil, Christoph Schwarze, Jan Gosheger, Georg Moellenbeck, Burkhard Schneider, Kristian Nikolaus Deventer, Niklas Klingebiel, Sebastian Grammatopoulos, George Boettner, Friedrich Schmidt-Braekling, Tom Cancers (Basel) Review SIMPLE SUMMARY: Malignant bone and soft tissue tumors are usually surgically removed with an envelope of healthy tissue as a barrier. If located in the long bones of the upper and lower extremity, this approach leads to a large bone defect commonly affecting a joint. One way to rebuild the bone defect and the neighboring joint is the use of a megaprosthesis that is anchored in the remaining bone comparable to a conventional joint replacement. In general this approach is popular as it provides early stability and allows the affected patient to begin rehabilitation early on. However, complications leading to long-term unplanned reoperation are common. This article provides an overview of current implant survival, types of complication and long-term outcomes of megaprostheses used following tumor resection. ABSTRACT: Megaprosthetic reconstruction of segmental bone defects following sarcoma resection is a frequently chosen surgical approach in orthopedic oncology. While the use of megaprostheses has gained popularity over the last decades and such implants are increasingly used for metastatic reconstructions and in non-tumor cases, there still is a high risk of long-term complications leading to revision surgery. This article investigates current implant survivorship, frequency and types of complications as well as functional outcomes of upper and lower limb megaprosthetic reconstructions. MDPI 2022-01-11 /pmc/articles/PMC8773828/ /pubmed/35053514 http://dx.doi.org/10.3390/cancers14020351 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Theil, Christoph Schwarze, Jan Gosheger, Georg Moellenbeck, Burkhard Schneider, Kristian Nikolaus Deventer, Niklas Klingebiel, Sebastian Grammatopoulos, George Boettner, Friedrich Schmidt-Braekling, Tom Implant Survival, Clinical Outcome and Complications of Megaprosthetic Reconstructions Following Sarcoma Resection |
title | Implant Survival, Clinical Outcome and Complications of Megaprosthetic Reconstructions Following Sarcoma Resection |
title_full | Implant Survival, Clinical Outcome and Complications of Megaprosthetic Reconstructions Following Sarcoma Resection |
title_fullStr | Implant Survival, Clinical Outcome and Complications of Megaprosthetic Reconstructions Following Sarcoma Resection |
title_full_unstemmed | Implant Survival, Clinical Outcome and Complications of Megaprosthetic Reconstructions Following Sarcoma Resection |
title_short | Implant Survival, Clinical Outcome and Complications of Megaprosthetic Reconstructions Following Sarcoma Resection |
title_sort | implant survival, clinical outcome and complications of megaprosthetic reconstructions following sarcoma resection |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773828/ https://www.ncbi.nlm.nih.gov/pubmed/35053514 http://dx.doi.org/10.3390/cancers14020351 |
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