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Optical Hydrogel Detector for pH Measurements
Measuring pH has become a major key for determining health conditions, and food safety. The traditional pH assessment approaches are costly and offer low sensitivity. Here, a novel pH sensor based on a pH-responsive hydrogel has been developed. A Fresnel lens pattern was replicated on the surface of...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773850/ https://www.ncbi.nlm.nih.gov/pubmed/35049668 http://dx.doi.org/10.3390/bios12010040 |
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author | Alqurashi, Yousef Elsherif, Mohamed Hendi, Asail Essa, Khamis Butt, Haider |
author_facet | Alqurashi, Yousef Elsherif, Mohamed Hendi, Asail Essa, Khamis Butt, Haider |
author_sort | Alqurashi, Yousef |
collection | PubMed |
description | Measuring pH has become a major key for determining health conditions, and food safety. The traditional pH assessment approaches are costly and offer low sensitivity. Here, a novel pH sensor based on a pH-responsive hydrogel has been developed. A Fresnel lens pattern was replicated on the surface of the pH-responsive hydrogel using the replica mould method. The pH sensors were tested in a pH range of 4–7. Introducing various pH solutions to the pH sensor led to volumetric shifts as the hydrogel swelled with pH. Consequently, the dimensions of the replicated Fresnel lens changed, modifying the focal length and the focus efficiency of the optical sensor. As a result, the measured optical power at a fixed distance from the sensor changed with pH. The optical sensor showed the best performance in the acidic region when pH changed from 4.5 to 5.5, in which the recorded power increased by 13%. The sensor exhibited high sensitivity to pH changes with a short respond time in a reversible manner. The developed pH optical sensor may have applications in medical point-of-care diagnostics and wearable continuous pH detection devices. |
format | Online Article Text |
id | pubmed-8773850 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87738502022-01-21 Optical Hydrogel Detector for pH Measurements Alqurashi, Yousef Elsherif, Mohamed Hendi, Asail Essa, Khamis Butt, Haider Biosensors (Basel) Article Measuring pH has become a major key for determining health conditions, and food safety. The traditional pH assessment approaches are costly and offer low sensitivity. Here, a novel pH sensor based on a pH-responsive hydrogel has been developed. A Fresnel lens pattern was replicated on the surface of the pH-responsive hydrogel using the replica mould method. The pH sensors were tested in a pH range of 4–7. Introducing various pH solutions to the pH sensor led to volumetric shifts as the hydrogel swelled with pH. Consequently, the dimensions of the replicated Fresnel lens changed, modifying the focal length and the focus efficiency of the optical sensor. As a result, the measured optical power at a fixed distance from the sensor changed with pH. The optical sensor showed the best performance in the acidic region when pH changed from 4.5 to 5.5, in which the recorded power increased by 13%. The sensor exhibited high sensitivity to pH changes with a short respond time in a reversible manner. The developed pH optical sensor may have applications in medical point-of-care diagnostics and wearable continuous pH detection devices. MDPI 2022-01-13 /pmc/articles/PMC8773850/ /pubmed/35049668 http://dx.doi.org/10.3390/bios12010040 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Alqurashi, Yousef Elsherif, Mohamed Hendi, Asail Essa, Khamis Butt, Haider Optical Hydrogel Detector for pH Measurements |
title | Optical Hydrogel Detector for pH Measurements |
title_full | Optical Hydrogel Detector for pH Measurements |
title_fullStr | Optical Hydrogel Detector for pH Measurements |
title_full_unstemmed | Optical Hydrogel Detector for pH Measurements |
title_short | Optical Hydrogel Detector for pH Measurements |
title_sort | optical hydrogel detector for ph measurements |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773850/ https://www.ncbi.nlm.nih.gov/pubmed/35049668 http://dx.doi.org/10.3390/bios12010040 |
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