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EvoMBN: Evolving Multi-Branch Networks on Myocardial Infarction Diagnosis Using 12-Lead Electrocardiograms

Multi-branch Networks (MBNs) have been successfully applied to myocardial infarction (MI) diagnosis using 12-lead electrocardiograms. However, most existing MBNs share a fixed architecture. The absence of architecture optimization has become a significant obstacle to a more accurate diagnosis for th...

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Detalles Bibliográficos
Autores principales: Liu, Wenhan, Ji, Jiewei, Chang, Sheng, Wang, Hao, He, Jin, Huang, Qijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773852/
https://www.ncbi.nlm.nih.gov/pubmed/35049642
http://dx.doi.org/10.3390/bios12010015
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author Liu, Wenhan
Ji, Jiewei
Chang, Sheng
Wang, Hao
He, Jin
Huang, Qijun
author_facet Liu, Wenhan
Ji, Jiewei
Chang, Sheng
Wang, Hao
He, Jin
Huang, Qijun
author_sort Liu, Wenhan
collection PubMed
description Multi-branch Networks (MBNs) have been successfully applied to myocardial infarction (MI) diagnosis using 12-lead electrocardiograms. However, most existing MBNs share a fixed architecture. The absence of architecture optimization has become a significant obstacle to a more accurate diagnosis for these MBNs. In this paper, an evolving neural network named EvoMBN is proposed for MI diagnosis. It utilizes a genetic algorithm (GA) to automatically learn the optimal MBN architectures. A novel fixed-length encoding method is proposed to represent each architecture. In addition, the crossover, mutation, selection, and fitness evaluation of the GA are defined to ensure the architecture can be optimized through evolutional iterations. A novel Lead Squeeze and Excitation (LSE) block is designed to summarize features from all the branch networks. It consists of a fully-connected layer and an LSE mechanism that assigns weights to different leads. Five-fold inter-patient cross validation experiments on MI detection and localization are performed using the PTB diagnostic database. Moreover, the model architecture learned from the PTB database is transferred to the PTB-XL database without any changes. Compared with existing studies, our EvoMBN shows superior generalization and the efficiency of its flexible architecture is suitable for auxiliary MI diagnosis in real-world.
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spelling pubmed-87738522022-01-21 EvoMBN: Evolving Multi-Branch Networks on Myocardial Infarction Diagnosis Using 12-Lead Electrocardiograms Liu, Wenhan Ji, Jiewei Chang, Sheng Wang, Hao He, Jin Huang, Qijun Biosensors (Basel) Article Multi-branch Networks (MBNs) have been successfully applied to myocardial infarction (MI) diagnosis using 12-lead electrocardiograms. However, most existing MBNs share a fixed architecture. The absence of architecture optimization has become a significant obstacle to a more accurate diagnosis for these MBNs. In this paper, an evolving neural network named EvoMBN is proposed for MI diagnosis. It utilizes a genetic algorithm (GA) to automatically learn the optimal MBN architectures. A novel fixed-length encoding method is proposed to represent each architecture. In addition, the crossover, mutation, selection, and fitness evaluation of the GA are defined to ensure the architecture can be optimized through evolutional iterations. A novel Lead Squeeze and Excitation (LSE) block is designed to summarize features from all the branch networks. It consists of a fully-connected layer and an LSE mechanism that assigns weights to different leads. Five-fold inter-patient cross validation experiments on MI detection and localization are performed using the PTB diagnostic database. Moreover, the model architecture learned from the PTB database is transferred to the PTB-XL database without any changes. Compared with existing studies, our EvoMBN shows superior generalization and the efficiency of its flexible architecture is suitable for auxiliary MI diagnosis in real-world. MDPI 2021-12-29 /pmc/articles/PMC8773852/ /pubmed/35049642 http://dx.doi.org/10.3390/bios12010015 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Liu, Wenhan
Ji, Jiewei
Chang, Sheng
Wang, Hao
He, Jin
Huang, Qijun
EvoMBN: Evolving Multi-Branch Networks on Myocardial Infarction Diagnosis Using 12-Lead Electrocardiograms
title EvoMBN: Evolving Multi-Branch Networks on Myocardial Infarction Diagnosis Using 12-Lead Electrocardiograms
title_full EvoMBN: Evolving Multi-Branch Networks on Myocardial Infarction Diagnosis Using 12-Lead Electrocardiograms
title_fullStr EvoMBN: Evolving Multi-Branch Networks on Myocardial Infarction Diagnosis Using 12-Lead Electrocardiograms
title_full_unstemmed EvoMBN: Evolving Multi-Branch Networks on Myocardial Infarction Diagnosis Using 12-Lead Electrocardiograms
title_short EvoMBN: Evolving Multi-Branch Networks on Myocardial Infarction Diagnosis Using 12-Lead Electrocardiograms
title_sort evombn: evolving multi-branch networks on myocardial infarction diagnosis using 12-lead electrocardiograms
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773852/
https://www.ncbi.nlm.nih.gov/pubmed/35049642
http://dx.doi.org/10.3390/bios12010015
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