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Influence of Particle Size on Ecotoxicity of Low-Density Polyethylene Microplastics, with and without Adsorbed Benzo-a-Pyrene, in Clam Scrobicularia plana
This study investigated the ecotoxicological effects of differently sized (4–6 µm and 20–25 µm) low-density polyethylene (LDPE) microplastics (MPs), with and without adsorbed benzo-a-pyrene (BaP), in clam Scrobicularia plana. Biomarkers of oxidative stress (superoxide dismutase—SOD; catalase—CAT), b...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773861/ https://www.ncbi.nlm.nih.gov/pubmed/35053226 http://dx.doi.org/10.3390/biom12010078 |
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author | Rodrigues, Ana Rita Mestre, Nélia C. C. da Fonseca, Tainá Garcia Pedro, Paulo Z. Carteny, Camilla C. Cormier, Bettie Keiter, Steffen Bebianno, Maria João |
author_facet | Rodrigues, Ana Rita Mestre, Nélia C. C. da Fonseca, Tainá Garcia Pedro, Paulo Z. Carteny, Camilla C. Cormier, Bettie Keiter, Steffen Bebianno, Maria João |
author_sort | Rodrigues, Ana Rita |
collection | PubMed |
description | This study investigated the ecotoxicological effects of differently sized (4–6 µm and 20–25 µm) low-density polyethylene (LDPE) microplastics (MPs), with and without adsorbed benzo-a-pyrene (BaP), in clam Scrobicularia plana. Biomarkers of oxidative stress (superoxide dismutase—SOD; catalase—CAT), biotransformation (glutathione-S-transferases—GST), oxidative damage (lipid peroxidation—LPO) and neurotoxicity (acetylcholinesterase—AChE) were analysed in gills and digestive glands at different time intervals for a total of 14 days of exposure. In order to have a better impact perspective of these contaminants, an integrated biomarker response index (IBR) and Health Index were applied. Biomarker alterations are apparently more related to smaller sized (4–6 µm) MPs in gills and to virgin LDPE MPs in the digestive gland according to IBR results, while the digestive gland was more affected by these MPs according to the health index. |
format | Online Article Text |
id | pubmed-8773861 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87738612022-01-21 Influence of Particle Size on Ecotoxicity of Low-Density Polyethylene Microplastics, with and without Adsorbed Benzo-a-Pyrene, in Clam Scrobicularia plana Rodrigues, Ana Rita Mestre, Nélia C. C. da Fonseca, Tainá Garcia Pedro, Paulo Z. Carteny, Camilla C. Cormier, Bettie Keiter, Steffen Bebianno, Maria João Biomolecules Article This study investigated the ecotoxicological effects of differently sized (4–6 µm and 20–25 µm) low-density polyethylene (LDPE) microplastics (MPs), with and without adsorbed benzo-a-pyrene (BaP), in clam Scrobicularia plana. Biomarkers of oxidative stress (superoxide dismutase—SOD; catalase—CAT), biotransformation (glutathione-S-transferases—GST), oxidative damage (lipid peroxidation—LPO) and neurotoxicity (acetylcholinesterase—AChE) were analysed in gills and digestive glands at different time intervals for a total of 14 days of exposure. In order to have a better impact perspective of these contaminants, an integrated biomarker response index (IBR) and Health Index were applied. Biomarker alterations are apparently more related to smaller sized (4–6 µm) MPs in gills and to virgin LDPE MPs in the digestive gland according to IBR results, while the digestive gland was more affected by these MPs according to the health index. MDPI 2022-01-05 /pmc/articles/PMC8773861/ /pubmed/35053226 http://dx.doi.org/10.3390/biom12010078 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Rodrigues, Ana Rita Mestre, Nélia C. C. da Fonseca, Tainá Garcia Pedro, Paulo Z. Carteny, Camilla C. Cormier, Bettie Keiter, Steffen Bebianno, Maria João Influence of Particle Size on Ecotoxicity of Low-Density Polyethylene Microplastics, with and without Adsorbed Benzo-a-Pyrene, in Clam Scrobicularia plana |
title | Influence of Particle Size on Ecotoxicity of Low-Density Polyethylene Microplastics, with and without Adsorbed Benzo-a-Pyrene, in Clam Scrobicularia plana |
title_full | Influence of Particle Size on Ecotoxicity of Low-Density Polyethylene Microplastics, with and without Adsorbed Benzo-a-Pyrene, in Clam Scrobicularia plana |
title_fullStr | Influence of Particle Size on Ecotoxicity of Low-Density Polyethylene Microplastics, with and without Adsorbed Benzo-a-Pyrene, in Clam Scrobicularia plana |
title_full_unstemmed | Influence of Particle Size on Ecotoxicity of Low-Density Polyethylene Microplastics, with and without Adsorbed Benzo-a-Pyrene, in Clam Scrobicularia plana |
title_short | Influence of Particle Size on Ecotoxicity of Low-Density Polyethylene Microplastics, with and without Adsorbed Benzo-a-Pyrene, in Clam Scrobicularia plana |
title_sort | influence of particle size on ecotoxicity of low-density polyethylene microplastics, with and without adsorbed benzo-a-pyrene, in clam scrobicularia plana |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773861/ https://www.ncbi.nlm.nih.gov/pubmed/35053226 http://dx.doi.org/10.3390/biom12010078 |
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