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Acetyltransferases GCN5 and PCAF Are Required for B Lymphocyte Maturation in Mice
B lymphocyte development has two DNA recombination processes: V(D)J recombination of the immunoglobulin (Igh) gene variable region, and class switching of the Igh constant regions from IgM to IgG, IgA, or IgE. V(D)J recombination is required for the successful maturation of B cells from pro-B to pre...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773862/ https://www.ncbi.nlm.nih.gov/pubmed/35053209 http://dx.doi.org/10.3390/biom12010061 |