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RTP801/REDD1 Is Involved in Neuroinflammation and Modulates Cognitive Dysfunction in Huntington’s Disease
RTP801/REDD1 is a stress-regulated protein whose levels are increased in several neurodegenerative diseases such as Parkinson’s, Alzheimer’s, and Huntington’s diseases (HD). RTP801 downregulation ameliorates behavioral abnormalities in several mouse models of these disorders. In HD, RTP801 mediates...
Autores principales: | Pérez-Sisqués, Leticia, Solana-Balaguer, Júlia, Campoy-Campos, Genís, Martín-Flores, Núria, Sancho-Balsells, Anna, Vives-Isern, Marcel, Soler-Palazón, Ferran, Garcia-Forn, Marta, Masana, Mercè, Alberch, Jordi, Pérez-Navarro, Esther, Giralt, Albert, Malagelada, Cristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773874/ https://www.ncbi.nlm.nih.gov/pubmed/35053183 http://dx.doi.org/10.3390/biom12010034 |
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