Cargando…

Sacsin Deletion Induces Aggregation of Glial Intermediate Filaments

Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a neurodegenerative disorder commonly diagnosed in infants and characterized by progressive cerebellar ataxia, spasticity, motor sensory neuropathy and axonal demyelination. ARSACS is caused by mutations in the SACS gene that lead...

Descripción completa

Detalles Bibliográficos
Autores principales:	Murtinheira, Fernanda, Migueis, Mafalda, Letra-Vilela, Ricardo, Diallo, Mickael, Quezada, Andrea, Valente, Cláudia A., Oliva, Abel, Rodriguez, Carmen, Martin, Vanesa, Herrera, Federico
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773934/ https://www.ncbi.nlm.nih.gov/pubmed/35053415 http://dx.doi.org/10.3390/cells11020299

Ejemplares similares

The J Domain of Sacsin Disrupts Intermediate Filament Assembly
por: Dabbaghizadeh, Afrooz, et al.
Publicado: (2022)

Altered organization of the intermediate filament cytoskeleton and relocalization of proteostasis modulators in cells lacking the ataxia protein sacsin
por: Duncan, Emma J., et al.
Publicado: (2017)

Citrullination of glial intermediate filaments is an early response in retinal injury
por: Wizeman, John W., et al.
Publicado: (2016)

High-Throughput Screening for Ligands of the HEPN Domain of Sacsin
por: Li, Xinlu, et al.
Publicado: (2015)

Can asymmetric post‐translational modifications regulate the behavior of STAT3 homodimers?
por: Letra‐Vilela, Ricardo, et al.
Publicado: (2020)

The role of gigaxonin in the degradation of the glial-specific intermediate filament protein GFAP
por: Lin, Ni-Hsuan, et al.
Publicado: (2016)

Efficient Neuroprotective Rescue of Sacsin-Related Disease Phenotypes in Zebrafish
por: Naef, Valentina, et al.
Publicado: (2021)

Antibodies to neurofilament, glial filament, and fibroblast intermediate filament proteins bind to different cell types of the nervous system
Publicado: (1981)

Two divergent haplogroups of a sacsin-like gene in Acropora corals
por: Takahashi-Kariyazono, Shiho, et al.
Publicado: (2021)

Assessment of Sacsin Turnover in Patients With ARSACS: Implications for Molecular Diagnosis and Pathogenesis
por: Longo, Fabiana, et al.
Publicado: (2021)

Co-expression of intermediate filaments glial fibrillary acidic protein and cytokeratin in pituitary adenoma
por: Wiesnagrotzki, Nina, et al.
Publicado: (2020)

Deletions in epidermal keratins leading to alterations in filament organization in vivo and in intermediate filament assembly in vitro
Publicado: (1990)

Genetics of Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS) and Role of Sacsin in Neurodegeneration
por: Bagaria, Jaya, et al.
Publicado: (2022)

The ARSACS disease protein sacsin controls lysosomal positioning and reformation by regulating microtubule dynamics
por: Francis, Vincent, et al.
Publicado: (2022)

Intermediate filaments
por: Steinert, P. M., et al.
Publicado: (1984)

Comparative Analysis and Functional Mapping of SACS Mutations Reveal Novel Insights into Sacsin Repeated Architecture
por: Romano, Alessandro, et al.
Publicado: (2013)

Functional Transcriptome Analysis in ARSACS KO Cell Model Reveals a Role of Sacsin in Autophagy
por: Morani, Federica, et al.
Publicado: (2019)

Multi-omic profiling reveals the ataxia protein sacsin is required for integrin trafficking and synaptic organization
por: Romano, Lisa E.L., et al.
Publicado: (2022)

Correction: The ARSACS disease protein sacsin controls lysosomal positioning and reformation by regulating microtubule dynamics
por: Francis, Vincent, et al.
Publicado: (2022)

Intermediate Filaments on the Move
por: Chou, Ying-Hao, et al.
Publicado: (2000)

The ataxia protein sacsin is a functional co-chaperone that protects against polyglutamine-expanded ataxin-1
por: Parfitt, David A., et al.
Publicado: (2009)

Dynamics of the neuronal intermediate filaments
Publicado: (1993)

Intermediate filaments in nervous tissues
por: Liem, RKH, et al.
Publicado: (1978)

Plasticity of Intermediate Filament Subunits
por: Kirmse, Robert, et al.
Publicado: (2010)

The Diversity of Intermediate Filaments in Astrocytes
por: Potokar, Maja, et al.
Publicado: (2020)

Capturing intermediate filament networks
por: Coulombe, Pierre A
Publicado: (2022)

Influence of phosphorylation on intermediate filaments
por: Kraxner, Julia, et al.
Publicado: (2023)

Purification of the 300K intermediate filament-associated protein and its in vitro recombination with intermediate filaments
Publicado: (1985)

Isolation and characterization of glial filaments from human brain
Publicado: (1978)

Brain postsynaptic densities: the relationship to glial and neuronal filaments
Publicado: (1980)

Assembly of type IV neuronal intermediate filaments in nonneuronal cells in the absence of preexisting cytoplasmic intermediate filaments
Publicado: (1993)

Intermediate filaments and the initiation of desmosome assembly
Publicado: (1985)

Dual regulation of intermediate filament phosphorylation
Publicado: (1984)

Correction: Plasticity of Intermediate Filament Subunits
por: Kirmse, Robert, et al.
Publicado: (2010)

Role of Intermediate Filaments in Vesicular Traffic
por: Margiotta, Azzurra, et al.
Publicado: (2016)

Intermediate Filaments and Polarization in the Intestinal Epithelium
por: Coch, Richard A., et al.
Publicado: (2016)

Paraneoplastic neuronal intermediate filament autoimmunity
por: Basal, Eati, et al.
Publicado: (2018)

Model for Bundling of Keratin Intermediate Filaments
por: Haimov, Ehud, et al.
Publicado: (2020)

Deimination, Intermediate Filaments and Associated Proteins
por: Briot, Julie, et al.
Publicado: (2020)

Gigaxonin is required for intermediate filament transport
por: Renganathan, Bhuvanasundar, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_5p7cphob93js9v07oemtdks6bl