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Nigella sativa L. Phytochemistry and Pharmacological Activities: A Review (2019–2021)

Medicinal and aromatic plants are mainly characterized by the presence of different bioactive compounds which exhibit various therapeutic activities. In order to investigate the different pharmacological properties of different Nigella sativa extracts, a multitude of research articles published in t...

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Detalles Bibliográficos
Autores principales: Dalli, Mohammed, Bekkouch, Oussama, Azizi, Salah-eddine, Azghar, Ali, Gseyra, Nadia, Kim, Bonglee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773974/
https://www.ncbi.nlm.nih.gov/pubmed/35053168
http://dx.doi.org/10.3390/biom12010020
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author Dalli, Mohammed
Bekkouch, Oussama
Azizi, Salah-eddine
Azghar, Ali
Gseyra, Nadia
Kim, Bonglee
author_facet Dalli, Mohammed
Bekkouch, Oussama
Azizi, Salah-eddine
Azghar, Ali
Gseyra, Nadia
Kim, Bonglee
author_sort Dalli, Mohammed
collection PubMed
description Medicinal and aromatic plants are mainly characterized by the presence of different bioactive compounds which exhibit various therapeutic activities. In order to investigate the different pharmacological properties of different Nigella sativa extracts, a multitude of research articles published in the period between 2019 and 2021 were obtained from different databases (Scopus, Science Direct, PubMed, and Web of Science), and then explored and analyzed. The analysis of the collected articles allows us to classify the phytochemicals and the pharmacological activities through their underlying molecular mechanisms, as well as to explore the pharmacological activities exhibited by several identified compounds in Nigella sativa which allow a better understanding, and better elucidation, of the bioactive compounds responsible for the pharmacological effects. Also shown are the existence of other bioactive compounds that are still unexplored and could be of great interest. This review could be taken as a guide for future studies in the field.
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spelling pubmed-87739742022-01-21 Nigella sativa L. Phytochemistry and Pharmacological Activities: A Review (2019–2021) Dalli, Mohammed Bekkouch, Oussama Azizi, Salah-eddine Azghar, Ali Gseyra, Nadia Kim, Bonglee Biomolecules Review Medicinal and aromatic plants are mainly characterized by the presence of different bioactive compounds which exhibit various therapeutic activities. In order to investigate the different pharmacological properties of different Nigella sativa extracts, a multitude of research articles published in the period between 2019 and 2021 were obtained from different databases (Scopus, Science Direct, PubMed, and Web of Science), and then explored and analyzed. The analysis of the collected articles allows us to classify the phytochemicals and the pharmacological activities through their underlying molecular mechanisms, as well as to explore the pharmacological activities exhibited by several identified compounds in Nigella sativa which allow a better understanding, and better elucidation, of the bioactive compounds responsible for the pharmacological effects. Also shown are the existence of other bioactive compounds that are still unexplored and could be of great interest. This review could be taken as a guide for future studies in the field. MDPI 2021-12-23 /pmc/articles/PMC8773974/ /pubmed/35053168 http://dx.doi.org/10.3390/biom12010020 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Dalli, Mohammed
Bekkouch, Oussama
Azizi, Salah-eddine
Azghar, Ali
Gseyra, Nadia
Kim, Bonglee
Nigella sativa L. Phytochemistry and Pharmacological Activities: A Review (2019–2021)
title Nigella sativa L. Phytochemistry and Pharmacological Activities: A Review (2019–2021)
title_full Nigella sativa L. Phytochemistry and Pharmacological Activities: A Review (2019–2021)
title_fullStr Nigella sativa L. Phytochemistry and Pharmacological Activities: A Review (2019–2021)
title_full_unstemmed Nigella sativa L. Phytochemistry and Pharmacological Activities: A Review (2019–2021)
title_short Nigella sativa L. Phytochemistry and Pharmacological Activities: A Review (2019–2021)
title_sort nigella sativa l. phytochemistry and pharmacological activities: a review (2019–2021)
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773974/
https://www.ncbi.nlm.nih.gov/pubmed/35053168
http://dx.doi.org/10.3390/biom12010020
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