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Extracellular HSP90α Induces MyD88-IRAK Complex-Associated IKKα/β−NF-κB/IRF3 and JAK2/TYK2−STAT-3 Signaling in Macrophages for Tumor-Promoting M2-Polarization

M2-polarization and the tumoricidal to tumor-promoting transition are commonly observed with tumor-infiltrating macrophages after interplay with cancer cells or/and other stroma cells. Our previous study indicated that macrophage M2-polarization can be induced by extracellular HSP90α (eHSP90α) secre...

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Detalles Bibliográficos
Autores principales:	Fan, Chi-Shuan, Chen, Chia-Chi, Chen, Li-Li, Chua, Kee Voon, Hung, Hui-Chen, Hsu, John T. -A., Huang, Tze-Sing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774043/ https://www.ncbi.nlm.nih.gov/pubmed/35053345 http://dx.doi.org/10.3390/cells11020229

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