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Post-Stroke Outcomes of Patients with Chronic Obstructive Pulmonary Disease

Introduction: Research has shown that patients with ischemic stroke and coexisting obstructive respiratory disorders have worse clinical status on admission and increased long-term mortality. Patients with chronic obstructive pulmonary disease (COPD) are at increased risk of stroke, and the risk is...

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Autores principales: Szylińska, Aleksandra, Kotfis, Katarzyna, Bott-Olejnik, Marta, Wańkowicz, Paweł, Rotter, Iwona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774103/
https://www.ncbi.nlm.nih.gov/pubmed/35053849
http://dx.doi.org/10.3390/brainsci12010106
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author Szylińska, Aleksandra
Kotfis, Katarzyna
Bott-Olejnik, Marta
Wańkowicz, Paweł
Rotter, Iwona
author_facet Szylińska, Aleksandra
Kotfis, Katarzyna
Bott-Olejnik, Marta
Wańkowicz, Paweł
Rotter, Iwona
author_sort Szylińska, Aleksandra
collection PubMed
description Introduction: Research has shown that patients with ischemic stroke and coexisting obstructive respiratory disorders have worse clinical status on admission and increased long-term mortality. Patients with chronic obstructive pulmonary disease (COPD) are at increased risk of stroke, and the risk is even greater after exacerbation of COPD. Moreover, COPD and stroke share major risk factors, which are advancing age and smoking. The aim of this study was to analyze the incidence of complications and mortality in acute ischemic stroke (AIS) patients with and without COPD. Material and methods: We analyzed prospectively collected data of 1022 patients with acute is-chemic stroke hospitalized in a district general hospital. The patients were divided into two groups—with coexisting COPD and without COPD. Results: Logistic regression analysis, which allowed for potential confounders, showed an association between coexisting COPD and the fol-lowing complications in acute ischemic stroke patients: heart failure (OR = 1.879, p = 0.048), atrial fibrillation (OR = 4.746, p = 0.012), delirium (OR = 2.803, p < 0.001), pneumonia (OR = 2.424, p = 0.005), bronchospasm (OR = 3.400, p = 0.023), and out-hospital mortality (OR = 2.656, p = 0.001). Conclusion: Patients presenting with acute ischemic stroke and coexisting COPD significantly more often had cardiac and pulmonary complications, as well as delirium following stroke. In a long-term follow-up, the probability of one-year survival was significantly lower in AIS patients with co-existing COPD.
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spelling pubmed-87741032022-01-21 Post-Stroke Outcomes of Patients with Chronic Obstructive Pulmonary Disease Szylińska, Aleksandra Kotfis, Katarzyna Bott-Olejnik, Marta Wańkowicz, Paweł Rotter, Iwona Brain Sci Article Introduction: Research has shown that patients with ischemic stroke and coexisting obstructive respiratory disorders have worse clinical status on admission and increased long-term mortality. Patients with chronic obstructive pulmonary disease (COPD) are at increased risk of stroke, and the risk is even greater after exacerbation of COPD. Moreover, COPD and stroke share major risk factors, which are advancing age and smoking. The aim of this study was to analyze the incidence of complications and mortality in acute ischemic stroke (AIS) patients with and without COPD. Material and methods: We analyzed prospectively collected data of 1022 patients with acute is-chemic stroke hospitalized in a district general hospital. The patients were divided into two groups—with coexisting COPD and without COPD. Results: Logistic regression analysis, which allowed for potential confounders, showed an association between coexisting COPD and the fol-lowing complications in acute ischemic stroke patients: heart failure (OR = 1.879, p = 0.048), atrial fibrillation (OR = 4.746, p = 0.012), delirium (OR = 2.803, p < 0.001), pneumonia (OR = 2.424, p = 0.005), bronchospasm (OR = 3.400, p = 0.023), and out-hospital mortality (OR = 2.656, p = 0.001). Conclusion: Patients presenting with acute ischemic stroke and coexisting COPD significantly more often had cardiac and pulmonary complications, as well as delirium following stroke. In a long-term follow-up, the probability of one-year survival was significantly lower in AIS patients with co-existing COPD. MDPI 2022-01-13 /pmc/articles/PMC8774103/ /pubmed/35053849 http://dx.doi.org/10.3390/brainsci12010106 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Szylińska, Aleksandra
Kotfis, Katarzyna
Bott-Olejnik, Marta
Wańkowicz, Paweł
Rotter, Iwona
Post-Stroke Outcomes of Patients with Chronic Obstructive Pulmonary Disease
title Post-Stroke Outcomes of Patients with Chronic Obstructive Pulmonary Disease
title_full Post-Stroke Outcomes of Patients with Chronic Obstructive Pulmonary Disease
title_fullStr Post-Stroke Outcomes of Patients with Chronic Obstructive Pulmonary Disease
title_full_unstemmed Post-Stroke Outcomes of Patients with Chronic Obstructive Pulmonary Disease
title_short Post-Stroke Outcomes of Patients with Chronic Obstructive Pulmonary Disease
title_sort post-stroke outcomes of patients with chronic obstructive pulmonary disease
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774103/
https://www.ncbi.nlm.nih.gov/pubmed/35053849
http://dx.doi.org/10.3390/brainsci12010106
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