The Limitation of the Combination of Transition State Theory and Thermodynamics for the Reactions of Proteins and Nucleic Acids

When a reaction is accompanied by a change with the speed close to or slower than the reaction rate, a circulating reaction flow can exist among the reaction states in the macroscopic stationary state. If the accompanying change were at equilibrium in the timescale of the relevant reaction, the tran...

Descripción completa

Detalles Bibliográficos
Autor principal: Shimamoto, Nobuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774198/
https://www.ncbi.nlm.nih.gov/pubmed/35053176
http://dx.doi.org/10.3390/biom12010028
_version_ 1784636279466491904
author Shimamoto, Nobuo
author_facet Shimamoto, Nobuo
author_sort Shimamoto, Nobuo
collection PubMed
description When a reaction is accompanied by a change with the speed close to or slower than the reaction rate, a circulating reaction flow can exist among the reaction states in the macroscopic stationary state. If the accompanying change were at equilibrium in the timescale of the relevant reaction, the transition-state theory would hold to eliminate the flow.
format Online
Article
Text
id pubmed-8774198
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-87741982022-01-21 The Limitation of the Combination of Transition State Theory and Thermodynamics for the Reactions of Proteins and Nucleic Acids Shimamoto, Nobuo Biomolecules Commentary When a reaction is accompanied by a change with the speed close to or slower than the reaction rate, a circulating reaction flow can exist among the reaction states in the macroscopic stationary state. If the accompanying change were at equilibrium in the timescale of the relevant reaction, the transition-state theory would hold to eliminate the flow. MDPI 2021-12-25 /pmc/articles/PMC8774198/ /pubmed/35053176 http://dx.doi.org/10.3390/biom12010028 Text en © 2021 by the author. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Commentary
Shimamoto, Nobuo
The Limitation of the Combination of Transition State Theory and Thermodynamics for the Reactions of Proteins and Nucleic Acids
title The Limitation of the Combination of Transition State Theory and Thermodynamics for the Reactions of Proteins and Nucleic Acids
title_full The Limitation of the Combination of Transition State Theory and Thermodynamics for the Reactions of Proteins and Nucleic Acids
title_fullStr The Limitation of the Combination of Transition State Theory and Thermodynamics for the Reactions of Proteins and Nucleic Acids
title_full_unstemmed The Limitation of the Combination of Transition State Theory and Thermodynamics for the Reactions of Proteins and Nucleic Acids
title_short The Limitation of the Combination of Transition State Theory and Thermodynamics for the Reactions of Proteins and Nucleic Acids
title_sort limitation of the combination of transition state theory and thermodynamics for the reactions of proteins and nucleic acids
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774198/
https://www.ncbi.nlm.nih.gov/pubmed/35053176
http://dx.doi.org/10.3390/biom12010028
work_keys_str_mv AT shimamotonobuo thelimitationofthecombinationoftransitionstatetheoryandthermodynamicsforthereactionsofproteinsandnucleicacids
AT shimamotonobuo limitationofthecombinationoftransitionstatetheoryandthermodynamicsforthereactionsofproteinsandnucleicacids

Ejemplares similares