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Transforming Growth Factor-β Activated Kinase 1 (Tak1) Is Activated in Hepatocellular Carcinoma, Mediates Tumor Progression, and Predicts Unfavorable Outcome

SIMPLE SUMMARY: Chronic inflammation is known to drive cancer initiation and progression in the liver and other organs. In different genetic mouse models, the role of the pro-inflammatory kinase Tak1 in liver cancer development has been controversial so far. To clarify the role of Tak1 in human hepa...

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Detalles Bibliográficos
Autores principales:	Ridder, Dirk Andreas, Urbansky, Lana Louisa, Witzel, Hagen Roland, Schindeldecker, Mario, Weinmann, Arndt, Berndt, Kristina, Gerber, Tiemo Sven, Köhler, Bruno Christian, Nichetti, Federico, Ludt, Annekathrin, Gehrke, Nadine, Schattenberg, Jörn Markus, Heinrich, Stefan, Roth, Wilfried, Straub, Beate Katharina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774263/ https://www.ncbi.nlm.nih.gov/pubmed/35053591 http://dx.doi.org/10.3390/cancers14020430

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