T Regulatory Cells in the Visceral Adipose Tissues

CD4(+) Foxp3(+) T regulatory cells (Tregs) residing in the visceral adipose tissues (VAT) have profound effects on local and systemic metabolism. Although many of the molecular characteristics of VAT resident Tregs have been identified, how these cells promote metabolic homeostasis is still unclear....

Descripción completa

Detalles Bibliográficos
Autores principales: Fooks, Allen N., D’Cruz, Louise M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774286/
https://www.ncbi.nlm.nih.gov/pubmed/35070445
http://dx.doi.org/10.20900/immunometab20220002
Descripción
Sumario:CD4(+) Foxp3(+) T regulatory cells (Tregs) residing in the visceral adipose tissues (VAT) have profound effects on local and systemic metabolism. Although many of the molecular characteristics of VAT resident Tregs have been identified, how these cells promote metabolic homeostasis is still unclear. Several new publications help to illuminate the molecular mechanisms that underpin VAT resident Treg function and will be discussed here.

Ejemplares similares