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A Deep Neural Network for Early Detection and Prediction of Chronic Kidney Disease

Diabetes and high blood pressure are the primary causes of Chronic Kidney Disease (CKD). Glomerular Filtration Rate (GFR) and kidney damage markers are used by researchers around the world to identify CKD as a condition that leads to reduced renal function over time. A person with CKD has a higher c...

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Autores principales: Singh, Vijendra, Asari, Vijayan K., Rajasekaran, Rajkumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774382/
https://www.ncbi.nlm.nih.gov/pubmed/35054287
http://dx.doi.org/10.3390/diagnostics12010116
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author Singh, Vijendra
Asari, Vijayan K.
Rajasekaran, Rajkumar
author_facet Singh, Vijendra
Asari, Vijayan K.
Rajasekaran, Rajkumar
author_sort Singh, Vijendra
collection PubMed
description Diabetes and high blood pressure are the primary causes of Chronic Kidney Disease (CKD). Glomerular Filtration Rate (GFR) and kidney damage markers are used by researchers around the world to identify CKD as a condition that leads to reduced renal function over time. A person with CKD has a higher chance of dying young. Doctors face a difficult task in diagnosing the different diseases linked to CKD at an early stage in order to prevent the disease. This research presents a novel deep learning model for the early detection and prediction of CKD. This research objectives to create a deep neural network and compare its performance to that of other contemporary machine learning techniques. In tests, the average of the associated features was used to replace all missing values in the database. After that, the neural network’s optimum parameters were fixed by establishing the parameters and running multiple trials. The foremost important features were selected by Recursive Feature Elimination (RFE). Hemoglobin, Specific Gravity, Serum Creatinine, Red Blood Cell Count, Albumin, Packed Cell Volume, and Hypertension were found as key features in the RFE. Selected features were passed to machine learning models for classification purposes. The proposed Deep neural model outperformed the other four classifiers (Support Vector Machine (SVM), K-Nearest Neighbor (KNN), Logistic regression, Random Forest, and Naive Bayes classifier) by achieving 100% accuracy. The proposed approach could be a useful tool for nephrologists in detecting CKD.
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spelling pubmed-87743822022-01-21 A Deep Neural Network for Early Detection and Prediction of Chronic Kidney Disease Singh, Vijendra Asari, Vijayan K. Rajasekaran, Rajkumar Diagnostics (Basel) Article Diabetes and high blood pressure are the primary causes of Chronic Kidney Disease (CKD). Glomerular Filtration Rate (GFR) and kidney damage markers are used by researchers around the world to identify CKD as a condition that leads to reduced renal function over time. A person with CKD has a higher chance of dying young. Doctors face a difficult task in diagnosing the different diseases linked to CKD at an early stage in order to prevent the disease. This research presents a novel deep learning model for the early detection and prediction of CKD. This research objectives to create a deep neural network and compare its performance to that of other contemporary machine learning techniques. In tests, the average of the associated features was used to replace all missing values in the database. After that, the neural network’s optimum parameters were fixed by establishing the parameters and running multiple trials. The foremost important features were selected by Recursive Feature Elimination (RFE). Hemoglobin, Specific Gravity, Serum Creatinine, Red Blood Cell Count, Albumin, Packed Cell Volume, and Hypertension were found as key features in the RFE. Selected features were passed to machine learning models for classification purposes. The proposed Deep neural model outperformed the other four classifiers (Support Vector Machine (SVM), K-Nearest Neighbor (KNN), Logistic regression, Random Forest, and Naive Bayes classifier) by achieving 100% accuracy. The proposed approach could be a useful tool for nephrologists in detecting CKD. MDPI 2022-01-05 /pmc/articles/PMC8774382/ /pubmed/35054287 http://dx.doi.org/10.3390/diagnostics12010116 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Singh, Vijendra
Asari, Vijayan K.
Rajasekaran, Rajkumar
A Deep Neural Network for Early Detection and Prediction of Chronic Kidney Disease
title A Deep Neural Network for Early Detection and Prediction of Chronic Kidney Disease
title_full A Deep Neural Network for Early Detection and Prediction of Chronic Kidney Disease
title_fullStr A Deep Neural Network for Early Detection and Prediction of Chronic Kidney Disease
title_full_unstemmed A Deep Neural Network for Early Detection and Prediction of Chronic Kidney Disease
title_short A Deep Neural Network for Early Detection and Prediction of Chronic Kidney Disease
title_sort deep neural network for early detection and prediction of chronic kidney disease
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774382/
https://www.ncbi.nlm.nih.gov/pubmed/35054287
http://dx.doi.org/10.3390/diagnostics12010116
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