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Infants of Mothers with Cocaine Use: Review of Clinical and Medico-Legal Aspects

Illicit drug use is a global problem that also affects pregnant women. Substance use and alcohol abuse during pregnancy may have various harmful consequences for both mothers and foetuses. Intrauterine exposure to illicit substances can be investigated through maternal reports and toxicological test...

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Detalles Bibliográficos
Autores principales: Cestonaro, Clara, Menozzi, Lorenzo, Terranova, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774427/
https://www.ncbi.nlm.nih.gov/pubmed/35053692
http://dx.doi.org/10.3390/children9010067
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author Cestonaro, Clara
Menozzi, Lorenzo
Terranova, Claudio
author_facet Cestonaro, Clara
Menozzi, Lorenzo
Terranova, Claudio
author_sort Cestonaro, Clara
collection PubMed
description Illicit drug use is a global problem that also affects pregnant women. Substance use and alcohol abuse during pregnancy may have various harmful consequences for both mothers and foetuses. Intrauterine exposure to illicit substances can be investigated through maternal reports and toxicological tests on mothers’ and/or newborns’ samples. While the negative effects of alcohol and opioid use on pregnancy, the foetus, and/or newborn are well established, the effects of cocaine use remain controversial. We performed a review of the literature to evaluate the current state of knowledge of the effects of intrauterine cocaine exposure on newborns’ and children’s long-term development and to highlight possible implications for health professionals dealing with women who use cocaine during pregnancy. Although intrauterine cocaine exposure has been associated with reduced infant measurements, no specific amount of cocaine use exerting such effects has been determined, and no long-term effects have been confirmed. The evidence of cocaine use during pregnancy justifies a clinical and social takeover of the mother and newborn without assuming that there will certainly be long-term damage related to intrauterine cocaine exposure, but also considering other possible associated factors.
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spelling pubmed-87744272022-01-21 Infants of Mothers with Cocaine Use: Review of Clinical and Medico-Legal Aspects Cestonaro, Clara Menozzi, Lorenzo Terranova, Claudio Children (Basel) Review Illicit drug use is a global problem that also affects pregnant women. Substance use and alcohol abuse during pregnancy may have various harmful consequences for both mothers and foetuses. Intrauterine exposure to illicit substances can be investigated through maternal reports and toxicological tests on mothers’ and/or newborns’ samples. While the negative effects of alcohol and opioid use on pregnancy, the foetus, and/or newborn are well established, the effects of cocaine use remain controversial. We performed a review of the literature to evaluate the current state of knowledge of the effects of intrauterine cocaine exposure on newborns’ and children’s long-term development and to highlight possible implications for health professionals dealing with women who use cocaine during pregnancy. Although intrauterine cocaine exposure has been associated with reduced infant measurements, no specific amount of cocaine use exerting such effects has been determined, and no long-term effects have been confirmed. The evidence of cocaine use during pregnancy justifies a clinical and social takeover of the mother and newborn without assuming that there will certainly be long-term damage related to intrauterine cocaine exposure, but also considering other possible associated factors. MDPI 2022-01-05 /pmc/articles/PMC8774427/ /pubmed/35053692 http://dx.doi.org/10.3390/children9010067 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Cestonaro, Clara
Menozzi, Lorenzo
Terranova, Claudio
Infants of Mothers with Cocaine Use: Review of Clinical and Medico-Legal Aspects
title Infants of Mothers with Cocaine Use: Review of Clinical and Medico-Legal Aspects
title_full Infants of Mothers with Cocaine Use: Review of Clinical and Medico-Legal Aspects
title_fullStr Infants of Mothers with Cocaine Use: Review of Clinical and Medico-Legal Aspects
title_full_unstemmed Infants of Mothers with Cocaine Use: Review of Clinical and Medico-Legal Aspects
title_short Infants of Mothers with Cocaine Use: Review of Clinical and Medico-Legal Aspects
title_sort infants of mothers with cocaine use: review of clinical and medico-legal aspects
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774427/
https://www.ncbi.nlm.nih.gov/pubmed/35053692
http://dx.doi.org/10.3390/children9010067
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