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Acute Mild Pancreatitis Following COVID-19 mRNA Vaccine in an Adolescent

A 17-year-old male was referred to the emergency room with sharp abdominal pain, pallor, sweating, and vomiting 12 h after the administration of his first Pfizer-BioNTech vaccine for coronavirus disease 2019 (COVID-19). He had abdominal pain, an increase in serum lipase value of > 3 times the upp...

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Autores principales: Kantar, Ahmad, Seminara, Manuela, Odoni, Marta, Dalla Verde, Ilaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774474/
https://www.ncbi.nlm.nih.gov/pubmed/35053654
http://dx.doi.org/10.3390/children9010029
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author Kantar, Ahmad
Seminara, Manuela
Odoni, Marta
Dalla Verde, Ilaria
author_facet Kantar, Ahmad
Seminara, Manuela
Odoni, Marta
Dalla Verde, Ilaria
author_sort Kantar, Ahmad
collection PubMed
description A 17-year-old male was referred to the emergency room with sharp abdominal pain, pallor, sweating, and vomiting 12 h after the administration of his first Pfizer-BioNTech vaccine for coronavirus disease 2019 (COVID-19). He had abdominal pain, an increase in serum lipase value of > 3 times the upper limits of normal, and magnetic resonance imaging (MRI) findings consistent with acute mild pancreatitis (AP). He was started on treatment with fluid therapy and non-steroidal anti-inflammatory drugs for pain management, after which he recovered rapidly and was discharged on the fourth day after hospitalization. The available data are difficult to interpret as AP is a relatively frequent disease, but its occurrence after vaccination seems extremely rare. Although it is a rare event, AP should be considered after COVID-19 vaccination, especially in those exhibiting abdominal tenderness and vomiting, which should be promptly treated and adequately investigated.
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spelling pubmed-87744742022-01-21 Acute Mild Pancreatitis Following COVID-19 mRNA Vaccine in an Adolescent Kantar, Ahmad Seminara, Manuela Odoni, Marta Dalla Verde, Ilaria Children (Basel) Case Report A 17-year-old male was referred to the emergency room with sharp abdominal pain, pallor, sweating, and vomiting 12 h after the administration of his first Pfizer-BioNTech vaccine for coronavirus disease 2019 (COVID-19). He had abdominal pain, an increase in serum lipase value of > 3 times the upper limits of normal, and magnetic resonance imaging (MRI) findings consistent with acute mild pancreatitis (AP). He was started on treatment with fluid therapy and non-steroidal anti-inflammatory drugs for pain management, after which he recovered rapidly and was discharged on the fourth day after hospitalization. The available data are difficult to interpret as AP is a relatively frequent disease, but its occurrence after vaccination seems extremely rare. Although it is a rare event, AP should be considered after COVID-19 vaccination, especially in those exhibiting abdominal tenderness and vomiting, which should be promptly treated and adequately investigated. MDPI 2021-12-31 /pmc/articles/PMC8774474/ /pubmed/35053654 http://dx.doi.org/10.3390/children9010029 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Kantar, Ahmad
Seminara, Manuela
Odoni, Marta
Dalla Verde, Ilaria
Acute Mild Pancreatitis Following COVID-19 mRNA Vaccine in an Adolescent
title Acute Mild Pancreatitis Following COVID-19 mRNA Vaccine in an Adolescent
title_full Acute Mild Pancreatitis Following COVID-19 mRNA Vaccine in an Adolescent
title_fullStr Acute Mild Pancreatitis Following COVID-19 mRNA Vaccine in an Adolescent
title_full_unstemmed Acute Mild Pancreatitis Following COVID-19 mRNA Vaccine in an Adolescent
title_short Acute Mild Pancreatitis Following COVID-19 mRNA Vaccine in an Adolescent
title_sort acute mild pancreatitis following covid-19 mrna vaccine in an adolescent
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774474/
https://www.ncbi.nlm.nih.gov/pubmed/35053654
http://dx.doi.org/10.3390/children9010029
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