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Epigenetic Silencing of Tumor Suppressor lncRNA NKILA: Implication on NF-κB Signaling in Non-Hodgkin’s Lymphoma

The long non-coding RNA (lncRNA) NKILA, localized to 20q13.31, is a negative regulator of NF-κB signaling implicated in carcinogenesis. As a CpG island is embedded in the promoter region of NKILA, it is hypothesized as a tumor suppressor lncRNA silenced by promoter DNA methylation in non-Hodgkin’s l...

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Detalles Bibliográficos
Autores principales:	Zhang, Min-Yue, Calin, George, Deng, Ming-Dan, Au-Yeung, Rex K. H., Wang, Lu-Qian, Chim, Chor-Sang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774545/ https://www.ncbi.nlm.nih.gov/pubmed/35052468 http://dx.doi.org/10.3390/genes13010128

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