Cargando…
Valorization of By-Products from Biofuel Biorefineries: Extraction and Purification of Bioactive Molecules from Post-Fermentation Corn Oil
The aim of this work was to develop innovative and sustainable extraction, concentration, and purification technologies aimed to recover target substances from corn oil, obtained as side stream product of biomass refineries. Residues of bioactive compounds such as carotenoids, phytosterols, tocopher...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774612/ https://www.ncbi.nlm.nih.gov/pubmed/35053885 http://dx.doi.org/10.3390/foods11020153 |
_version_ | 1784636390028345344 |
---|---|
author | Cairone, Francesco Cesa, Stefania Ciogli, Alessia Fabrizi, Giancarlo Goggiamani, Antonella Iazzetti, Antonia Di Lena, Gabriella Sanchez del Pulgar, Jose Lucarini, Massimo Cantò, Luca Zengin, Gokhan Ondrejíčková, Petra |
author_facet | Cairone, Francesco Cesa, Stefania Ciogli, Alessia Fabrizi, Giancarlo Goggiamani, Antonella Iazzetti, Antonia Di Lena, Gabriella Sanchez del Pulgar, Jose Lucarini, Massimo Cantò, Luca Zengin, Gokhan Ondrejíčková, Petra |
author_sort | Cairone, Francesco |
collection | PubMed |
description | The aim of this work was to develop innovative and sustainable extraction, concentration, and purification technologies aimed to recover target substances from corn oil, obtained as side stream product of biomass refineries. Residues of bioactive compounds such as carotenoids, phytosterols, tocopherols, and polyphenols could be extracted from this matrix and applied as ingredients for food and feeds, nutraceuticals, pharmaceuticals, and cosmetic products. These molecules are well known for their antioxidant and antiradical capacity, besides other specific biological activities, generically involved in the prevention of chronic and degenerative diseases. The project involved the development of methods for the selective extraction of these minor components, using as suitable extraction technique solid phase extraction. All the extracted and purified fractions were evaluated by NMR spectroscopic analyses and UV–Vis spectrophotometric techniques and characterized by quali-quantitative HPLC analyses. TPC (total phenolic content) and TFC (total flavonoid content) were also determined. DPPH and ABTS radical were used to evaluate radical quenching abilities. Acetylcholinesterase (AChE), amylase, glucosidase, and tyrosinase were selected as enzymes in the enzyme inhibitory assays. The obtained results showed the presence of a complex group of interesting molecules with strong potential in market applications according to circular economy principles. |
format | Online Article Text |
id | pubmed-8774612 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87746122022-01-21 Valorization of By-Products from Biofuel Biorefineries: Extraction and Purification of Bioactive Molecules from Post-Fermentation Corn Oil Cairone, Francesco Cesa, Stefania Ciogli, Alessia Fabrizi, Giancarlo Goggiamani, Antonella Iazzetti, Antonia Di Lena, Gabriella Sanchez del Pulgar, Jose Lucarini, Massimo Cantò, Luca Zengin, Gokhan Ondrejíčková, Petra Foods Article The aim of this work was to develop innovative and sustainable extraction, concentration, and purification technologies aimed to recover target substances from corn oil, obtained as side stream product of biomass refineries. Residues of bioactive compounds such as carotenoids, phytosterols, tocopherols, and polyphenols could be extracted from this matrix and applied as ingredients for food and feeds, nutraceuticals, pharmaceuticals, and cosmetic products. These molecules are well known for their antioxidant and antiradical capacity, besides other specific biological activities, generically involved in the prevention of chronic and degenerative diseases. The project involved the development of methods for the selective extraction of these minor components, using as suitable extraction technique solid phase extraction. All the extracted and purified fractions were evaluated by NMR spectroscopic analyses and UV–Vis spectrophotometric techniques and characterized by quali-quantitative HPLC analyses. TPC (total phenolic content) and TFC (total flavonoid content) were also determined. DPPH and ABTS radical were used to evaluate radical quenching abilities. Acetylcholinesterase (AChE), amylase, glucosidase, and tyrosinase were selected as enzymes in the enzyme inhibitory assays. The obtained results showed the presence of a complex group of interesting molecules with strong potential in market applications according to circular economy principles. MDPI 2022-01-07 /pmc/articles/PMC8774612/ /pubmed/35053885 http://dx.doi.org/10.3390/foods11020153 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Cairone, Francesco Cesa, Stefania Ciogli, Alessia Fabrizi, Giancarlo Goggiamani, Antonella Iazzetti, Antonia Di Lena, Gabriella Sanchez del Pulgar, Jose Lucarini, Massimo Cantò, Luca Zengin, Gokhan Ondrejíčková, Petra Valorization of By-Products from Biofuel Biorefineries: Extraction and Purification of Bioactive Molecules from Post-Fermentation Corn Oil |
title | Valorization of By-Products from Biofuel Biorefineries: Extraction and Purification of Bioactive Molecules from Post-Fermentation Corn Oil |
title_full | Valorization of By-Products from Biofuel Biorefineries: Extraction and Purification of Bioactive Molecules from Post-Fermentation Corn Oil |
title_fullStr | Valorization of By-Products from Biofuel Biorefineries: Extraction and Purification of Bioactive Molecules from Post-Fermentation Corn Oil |
title_full_unstemmed | Valorization of By-Products from Biofuel Biorefineries: Extraction and Purification of Bioactive Molecules from Post-Fermentation Corn Oil |
title_short | Valorization of By-Products from Biofuel Biorefineries: Extraction and Purification of Bioactive Molecules from Post-Fermentation Corn Oil |
title_sort | valorization of by-products from biofuel biorefineries: extraction and purification of bioactive molecules from post-fermentation corn oil |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774612/ https://www.ncbi.nlm.nih.gov/pubmed/35053885 http://dx.doi.org/10.3390/foods11020153 |
work_keys_str_mv | AT caironefrancesco valorizationofbyproductsfrombiofuelbiorefineriesextractionandpurificationofbioactivemoleculesfrompostfermentationcornoil AT cesastefania valorizationofbyproductsfrombiofuelbiorefineriesextractionandpurificationofbioactivemoleculesfrompostfermentationcornoil AT cioglialessia valorizationofbyproductsfrombiofuelbiorefineriesextractionandpurificationofbioactivemoleculesfrompostfermentationcornoil AT fabrizigiancarlo valorizationofbyproductsfrombiofuelbiorefineriesextractionandpurificationofbioactivemoleculesfrompostfermentationcornoil AT goggiamaniantonella valorizationofbyproductsfrombiofuelbiorefineriesextractionandpurificationofbioactivemoleculesfrompostfermentationcornoil AT iazzettiantonia valorizationofbyproductsfrombiofuelbiorefineriesextractionandpurificationofbioactivemoleculesfrompostfermentationcornoil AT dilenagabriella valorizationofbyproductsfrombiofuelbiorefineriesextractionandpurificationofbioactivemoleculesfrompostfermentationcornoil AT sanchezdelpulgarjose valorizationofbyproductsfrombiofuelbiorefineriesextractionandpurificationofbioactivemoleculesfrompostfermentationcornoil AT lucarinimassimo valorizationofbyproductsfrombiofuelbiorefineriesextractionandpurificationofbioactivemoleculesfrompostfermentationcornoil AT cantoluca valorizationofbyproductsfrombiofuelbiorefineriesextractionandpurificationofbioactivemoleculesfrompostfermentationcornoil AT zengingokhan valorizationofbyproductsfrombiofuelbiorefineriesextractionandpurificationofbioactivemoleculesfrompostfermentationcornoil AT ondrejickovapetra valorizationofbyproductsfrombiofuelbiorefineriesextractionandpurificationofbioactivemoleculesfrompostfermentationcornoil |