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Preparation of Curcumin Hydrogel Beads for the Development of Functional Kulfi: A Tailoring Delivery System

Curcumin has been demonstrated to have biological activities and its fortification in food products is an important strategy to deliver bioactive ingredients at target sites. However, studies have documented a curcumin low bioavailability and low intake. Hence, combining functional ingredients with...

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Autores principales: Sharma, Minaxi, Inbaraj, Baskaran Stephen, Dikkala, Praveen Kumar, Sridhar, Kandi, Mude, Arjun Naik, Narsaiah, Kairam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774899/
https://www.ncbi.nlm.nih.gov/pubmed/35053917
http://dx.doi.org/10.3390/foods11020182
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author Sharma, Minaxi
Inbaraj, Baskaran Stephen
Dikkala, Praveen Kumar
Sridhar, Kandi
Mude, Arjun Naik
Narsaiah, Kairam
author_facet Sharma, Minaxi
Inbaraj, Baskaran Stephen
Dikkala, Praveen Kumar
Sridhar, Kandi
Mude, Arjun Naik
Narsaiah, Kairam
author_sort Sharma, Minaxi
collection PubMed
description Curcumin has been demonstrated to have biological activities and its fortification in food products is an important strategy to deliver bioactive ingredients at target sites. However, studies have documented a curcumin low bioavailability and low intake. Hence, combining functional ingredients with food should be needed to prevent widespread nutrient intake shortfalls and associated deficiencies. Thus, curcumin was encapsulated in calcium-alginate and their characteristics as well as in vitro release behavior of curcumin hydrogel beads (CHBs) was studied. Moreover, CHBs were fortified in development of functional Kulfi and their quality characteristics were studied. The encapsulation efficiency was up to 95.04%, indicating that most of the curcumin was entrapped. FTIR shifts in the bands were due to the replacement of sodium ions to the calcium ions. In vitro release (%) for CHBs was found to be 67.15% after 2 h, which increased slightly up to 67.88% after 4 h. The average swelling index of CHBs was found to be 10.21 to 37.92 from 2 to 12 h in PBS (pH 7.40). Control and Kulfi fortified with CHBs showed no significant difference (p > 0.05) in colour (L = 73.03 and 75.88) and the melting rate (0.88 mL/min and 0.63 mL/min), respectively. Standard plate count was reduced in the Kulfi fortified with CHBs (13.77 × 10(4) CFU/mL) with high sensory score for overall acceptability (8.56) compared to the control (154.70 × 10(4) CFU/mL). These findings suggested the feasibility of developing CHBs to mask the bitterness, enhance the solubility, and increase the bioavailability in gastrointestinal conditions. Additionally, Kulfi could be a suitable dairy delivery system for curcumin bioactive compounds.
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spelling pubmed-87748992022-01-21 Preparation of Curcumin Hydrogel Beads for the Development of Functional Kulfi: A Tailoring Delivery System Sharma, Minaxi Inbaraj, Baskaran Stephen Dikkala, Praveen Kumar Sridhar, Kandi Mude, Arjun Naik Narsaiah, Kairam Foods Article Curcumin has been demonstrated to have biological activities and its fortification in food products is an important strategy to deliver bioactive ingredients at target sites. However, studies have documented a curcumin low bioavailability and low intake. Hence, combining functional ingredients with food should be needed to prevent widespread nutrient intake shortfalls and associated deficiencies. Thus, curcumin was encapsulated in calcium-alginate and their characteristics as well as in vitro release behavior of curcumin hydrogel beads (CHBs) was studied. Moreover, CHBs were fortified in development of functional Kulfi and their quality characteristics were studied. The encapsulation efficiency was up to 95.04%, indicating that most of the curcumin was entrapped. FTIR shifts in the bands were due to the replacement of sodium ions to the calcium ions. In vitro release (%) for CHBs was found to be 67.15% after 2 h, which increased slightly up to 67.88% after 4 h. The average swelling index of CHBs was found to be 10.21 to 37.92 from 2 to 12 h in PBS (pH 7.40). Control and Kulfi fortified with CHBs showed no significant difference (p > 0.05) in colour (L = 73.03 and 75.88) and the melting rate (0.88 mL/min and 0.63 mL/min), respectively. Standard plate count was reduced in the Kulfi fortified with CHBs (13.77 × 10(4) CFU/mL) with high sensory score for overall acceptability (8.56) compared to the control (154.70 × 10(4) CFU/mL). These findings suggested the feasibility of developing CHBs to mask the bitterness, enhance the solubility, and increase the bioavailability in gastrointestinal conditions. Additionally, Kulfi could be a suitable dairy delivery system for curcumin bioactive compounds. MDPI 2022-01-11 /pmc/articles/PMC8774899/ /pubmed/35053917 http://dx.doi.org/10.3390/foods11020182 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sharma, Minaxi
Inbaraj, Baskaran Stephen
Dikkala, Praveen Kumar
Sridhar, Kandi
Mude, Arjun Naik
Narsaiah, Kairam
Preparation of Curcumin Hydrogel Beads for the Development of Functional Kulfi: A Tailoring Delivery System
title Preparation of Curcumin Hydrogel Beads for the Development of Functional Kulfi: A Tailoring Delivery System
title_full Preparation of Curcumin Hydrogel Beads for the Development of Functional Kulfi: A Tailoring Delivery System
title_fullStr Preparation of Curcumin Hydrogel Beads for the Development of Functional Kulfi: A Tailoring Delivery System
title_full_unstemmed Preparation of Curcumin Hydrogel Beads for the Development of Functional Kulfi: A Tailoring Delivery System
title_short Preparation of Curcumin Hydrogel Beads for the Development of Functional Kulfi: A Tailoring Delivery System
title_sort preparation of curcumin hydrogel beads for the development of functional kulfi: a tailoring delivery system
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774899/
https://www.ncbi.nlm.nih.gov/pubmed/35053917
http://dx.doi.org/10.3390/foods11020182
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