Capturing SNP Association across the NK Receptor and HLA Gene Regions in Multiple Sclerosis by Targeted Penalised Regression Models

Conventional genome-wide association studies (GWASs) of complex traits, such as Multiple Sclerosis (MS), are reliant on per-SNP p-values and are therefore heavily burdened by multiple testing correction. Thus, in order to detect more subtle alterations, ever increasing sample sizes are required, whi...

Descripción completa

Detalles Bibliográficos
Autores principales: Burnard, Sean M., Lea, Rodney A., Benton, Miles, Eccles, David, Kennedy, Daniel W., Lechner-Scott, Jeannette, Scott, Rodney J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774935/
https://www.ncbi.nlm.nih.gov/pubmed/35052430
http://dx.doi.org/10.3390/genes13010087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774935/
https://www.ncbi.nlm.nih.gov/pubmed/35052430
http://dx.doi.org/10.3390/genes13010087

Ejemplares similares