Cargando…
Capturing SNP Association across the NK Receptor and HLA Gene Regions in Multiple Sclerosis by Targeted Penalised Regression Models
Conventional genome-wide association studies (GWASs) of complex traits, such as Multiple Sclerosis (MS), are reliant on per-SNP p-values and are therefore heavily burdened by multiple testing correction. Thus, in order to detect more subtle alterations, ever increasing sample sizes are required, whi...
Autores principales: | Burnard, Sean M., Lea, Rodney A., Benton, Miles, Eccles, David, Kennedy, Daniel W., Lechner-Scott, Jeannette, Scott, Rodney J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8774935/ https://www.ncbi.nlm.nih.gov/pubmed/35052430 http://dx.doi.org/10.3390/genes13010087 |
Ejemplares similares
-
Differential methylation at MHC in CD4(+) T cells is associated with multiple sclerosis independently of HLA-DRB1
por: Maltby, Vicki E., et al.
Publicado: (2017) -
Genome-wide DNA methylation changes in CD19(+) B cells from relapsing-remitting multiple sclerosis patients
por: Maltby, Vicki E., et al.
Publicado: (2018) -
Genome-wide DNA methylation profiling of CD8+ T cells shows a distinct epigenetic signature to CD4+ T cells in multiple sclerosis patients
por: Maltby, Vicki E., et al.
Publicado: (2015) -
Penalising Brownian paths
por: Roynette, Bernard, et al.
Publicado: (2009) -
Epigenetic differences at the HTR2A locus in progressive multiple sclerosis patients
por: Maltby, Vicki E., et al.
Publicado: (2020)