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Epigenome-Wide DNA Methylation Profiling in Colorectal Cancer and Normal Adjacent Colon Using Infinium Human Methylation 450K

The aims were to profile the DNA methylation in colorectal cancer (CRC) and to explore cancer-specific methylation biomarkers. Fifty-four pairs of CRCs and the adjacent normal tissues were subjected to Infinium Human Methylation 450K assay and analysed using ChAMP R package. A total of 26,093 differ...

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Detalles Bibliográficos
Autores principales: Baharudin, Rashidah, Ishak, Muhiddin, Muhamad Yusof, Azliana, Saidin, Sazuita, Syafruddin, Saiful Effendi, Wan Mohamad Nazarie, Wan Fahmi, Lee, Learn-Han, Ab Mutalib, Nurul-Syakima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775085/
https://www.ncbi.nlm.nih.gov/pubmed/35054365
http://dx.doi.org/10.3390/diagnostics12010198