Cargando…
Sleep Treatments in Disorders of Consciousness: A Systematic Review
Sleep disorders are among the main comorbidities in patients with a Disorder of Consciousness (DOC). Given the key role of sleep in neural and cognitive functioning, detecting and treating sleep disorders in DOCs might be an effective therapeutic strategy to boost consciousness recovery and levels o...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775271/ https://www.ncbi.nlm.nih.gov/pubmed/35054255 http://dx.doi.org/10.3390/diagnostics12010088 |
_version_ | 1784636545869807616 |
---|---|
author | Cacciatore, Martina Magnani, Francesca G. Leonardi, Matilde Rossi Sebastiano, Davide Sattin, Davide |
author_facet | Cacciatore, Martina Magnani, Francesca G. Leonardi, Matilde Rossi Sebastiano, Davide Sattin, Davide |
author_sort | Cacciatore, Martina |
collection | PubMed |
description | Sleep disorders are among the main comorbidities in patients with a Disorder of Consciousness (DOC). Given the key role of sleep in neural and cognitive functioning, detecting and treating sleep disorders in DOCs might be an effective therapeutic strategy to boost consciousness recovery and levels of awareness. To date, no systematic reviews have been conducted that explore the effect of sleep treatments in DOCs; thus, we systematically reviewed the existing studies on both pharmacological and non-pharmacological treatments for sleep disorders in DOCs. Among 2267 assessed articles, only 7 were included in the systematic review. The studies focused on two sleep disorder categories (sleep-related breathing disorders and circadian rhythm dysregulation) treated with both pharmacological (Modafinil and Intrathecal Baclofen) and non-pharmacological (positive airway pressure, bright light stimulation, and central thalamic deep brain stimulation) interventions. Although the limited number of studies and their heterogeneity do not allow generalized conclusions, all the studies highlighted the effectiveness of treatments on both sleep disorders and levels of awareness. For this reason, clinical and diagnostic evaluations able to detect sleep disorders in DOC patients should be adopted in the clinical routine for the purpose of intervening promptly with the most appropriate treatment. |
format | Online Article Text |
id | pubmed-8775271 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87752712022-01-21 Sleep Treatments in Disorders of Consciousness: A Systematic Review Cacciatore, Martina Magnani, Francesca G. Leonardi, Matilde Rossi Sebastiano, Davide Sattin, Davide Diagnostics (Basel) Systematic Review Sleep disorders are among the main comorbidities in patients with a Disorder of Consciousness (DOC). Given the key role of sleep in neural and cognitive functioning, detecting and treating sleep disorders in DOCs might be an effective therapeutic strategy to boost consciousness recovery and levels of awareness. To date, no systematic reviews have been conducted that explore the effect of sleep treatments in DOCs; thus, we systematically reviewed the existing studies on both pharmacological and non-pharmacological treatments for sleep disorders in DOCs. Among 2267 assessed articles, only 7 were included in the systematic review. The studies focused on two sleep disorder categories (sleep-related breathing disorders and circadian rhythm dysregulation) treated with both pharmacological (Modafinil and Intrathecal Baclofen) and non-pharmacological (positive airway pressure, bright light stimulation, and central thalamic deep brain stimulation) interventions. Although the limited number of studies and their heterogeneity do not allow generalized conclusions, all the studies highlighted the effectiveness of treatments on both sleep disorders and levels of awareness. For this reason, clinical and diagnostic evaluations able to detect sleep disorders in DOC patients should be adopted in the clinical routine for the purpose of intervening promptly with the most appropriate treatment. MDPI 2021-12-31 /pmc/articles/PMC8775271/ /pubmed/35054255 http://dx.doi.org/10.3390/diagnostics12010088 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Systematic Review Cacciatore, Martina Magnani, Francesca G. Leonardi, Matilde Rossi Sebastiano, Davide Sattin, Davide Sleep Treatments in Disorders of Consciousness: A Systematic Review |
title | Sleep Treatments in Disorders of Consciousness: A Systematic Review |
title_full | Sleep Treatments in Disorders of Consciousness: A Systematic Review |
title_fullStr | Sleep Treatments in Disorders of Consciousness: A Systematic Review |
title_full_unstemmed | Sleep Treatments in Disorders of Consciousness: A Systematic Review |
title_short | Sleep Treatments in Disorders of Consciousness: A Systematic Review |
title_sort | sleep treatments in disorders of consciousness: a systematic review |
topic | Systematic Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775271/ https://www.ncbi.nlm.nih.gov/pubmed/35054255 http://dx.doi.org/10.3390/diagnostics12010088 |
work_keys_str_mv | AT cacciatoremartina sleeptreatmentsindisordersofconsciousnessasystematicreview AT magnanifrancescag sleeptreatmentsindisordersofconsciousnessasystematicreview AT leonardimatilde sleeptreatmentsindisordersofconsciousnessasystematicreview AT rossisebastianodavide sleeptreatmentsindisordersofconsciousnessasystematicreview AT sattindavide sleeptreatmentsindisordersofconsciousnessasystematicreview |