A Complexed Crystal Structure of a Single-Stranded DNA-Binding Protein with Quercetin and the Structural Basis of Flavonol Inhibition Specificity

Single-stranded DNA (ssDNA)-binding protein (SSB) plays a crucial role in DNA replication, repair, and recombination as well as replication fork restarts. SSB is essential for cell survival and, thus, is an attractive target for potential antipathogen chemotherapy. Whether naturally occurring produc...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, En-Shyh, Luo, Ren-Hong, Huang, Cheng-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775380/
https://www.ncbi.nlm.nih.gov/pubmed/35054774
http://dx.doi.org/10.3390/ijms23020588

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775380/
https://www.ncbi.nlm.nih.gov/pubmed/35054774
http://dx.doi.org/10.3390/ijms23020588

Ejemplares similares