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Genetic Distribution of Five Spinocerebellar Ataxia Microsatellite Loci in Mexican Native American Populations and Its Impact on Contemporary Mestizo Populations
Spinocerebellar ataxias (SCAs) conform a heterogeneous group of neurodegenerative disorders with autosomal dominant inheritance. Five of the most frequent SCAs are caused by a CAG repeat expansion in the exons of specific genes. The SCAs incidence and the distribution of polymorphic CAG alleles vary...
Autores principales: | Gómez, Rocío, Tapia-Guerrero, Yessica S., Cisneros, Bulmaro, Orozco, Lorena, Cerecedo-Zapata, César, Mendoza-Caamal, Elvia, Leyva-Gómez, Gerardo, Leyva-García, Norberto, Velázquez-Pérez, Luis, Magaña, Jonathan J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775409/ https://www.ncbi.nlm.nih.gov/pubmed/35052497 http://dx.doi.org/10.3390/genes13010157 |
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