Identification and Characterization of an Exonic Duplication in PALB2 in a Man with Synchronous Breast and Prostate Cancer

PALB2 (partner and localizer of BRCA2), as indicated by its name, is a BRCA2-interacting protein that plays an important role in homologous recombination (HR) and DNA double-strand break (DSB) repair. While pathogenic variants of PALB2 have been well proven to confer an increased risk of breast canc...

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Detalles Bibliográficos
Autores principales: Bouras, Ahmed, Lafaye, Cyril, Leone, Melanie, Kherraf, Zine-Eddine, Martin-Denavit, Tanguy, Fert-Ferrer, Sandra, Calender, Alain, Boutry-Kryza, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775416/
https://www.ncbi.nlm.nih.gov/pubmed/35054852
http://dx.doi.org/10.3390/ijms23020667

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