Cargando…

High-Throughput 3D Tumor Spheroid Array Platform for Evaluating Sensitivity of Proton-Drug Combinations

Proton beam therapy (PBT) is a critical treatment modality for head and neck squamous cell carcinoma (HNSCC). However, not much is known about drug combinations that may improve the efficacy of PBT. This study aimed to test the feasibility of a three-dimensional (3D) tumor-spheroid-based high-throug...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Dong Woo, Kim, Jung Eun, Lee, Ga-Haeng, Son, Arang, Park, Hee Chul, Oh, Dongryul, Jo, Kwanghyun, Choi, Changhoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775525/ https://www.ncbi.nlm.nih.gov/pubmed/35054773 http://dx.doi.org/10.3390/ijms23020587

Ejemplares similares

Valproic Acid Sensitizes Hepatocellular Carcinoma Cells to Proton Therapy by Suppressing NRF2 Activation
por: Yu, Jeong Il, et al.
Publicado: (2017)

Publisher Correction: Valproic Acid Sensitizes Hepatocellular Carcinoma Cells to Proton Therapy by Suppressing NRF2 Activation
por: Yu, Jeong Il, et al.
Publicado: (2018)

Downregulation of Mcl-1 by Panobinostat Potentiates Proton Beam Therapy in Hepatocellular Carcinoma Cells
por: Choi, Changhoon, et al.
Publicado: (2021)

Targeting DNA-dependent protein kinase sensitizes hepatocellular carcinoma cells to proton beam irradiation through apoptosis induction
por: Choi, Changhoon, et al.
Publicado: (2019)

Pitch-tunable pillar arrays for high-throughput culture and immunohistological analysis of tumor spheroids
por: Lee, Dong Woo, et al.
Publicado: (2018)

A Cancer Spheroid Array Chip for Selecting Effective Drug
por: Choi, Jae Won, et al.
Publicado: (2019)

Radiosensitization by Marine Sponge Agelas sp. Extracts in Hepatocellular Carcinoma Cells with Autophagy Induction
por: Choi, Changhoon, et al.
Publicado: (2018)

Early clinical outcomes of helical tomotherapy/intensity‐modulated proton therapy combination in nasopharynx cancer
por: Park, Seung Gyu, et al.
Publicado: (2019)

Isolation of Scalarane-Type Sesterterpenoids from the Marine Sponge Dysidea sp. and Stereochemical Reassignment of 12-epi-Phyllactone D/E
por: Shin, A-Young, et al.
Publicado: (2021)

Manganese Ferrite Nanoparticles Enhance the Sensitivity of Hepa1-6 Hepatocellular Carcinoma to Radiation by Remodeling Tumor Microenvironments
por: Shin, Sung-Won, et al.
Publicado: (2021)

Therapeutic Potential of (−)-Agelamide D, a Diterpene Alkaloid from the Marine Sponge Agelas sp., as a Natural Radiosensitizer in Hepatocellular Carcinoma Models
por: Choi, Changhoon, et al.
Publicado: (2020)

Toxicity of Proton Therapy versus Photon Therapy on Salvage Re-Irradiation for Non-Small Cell Lung Cancer
por: Yang, Kyungmi, et al.
Publicado: (2022)

An Automated High-Throughput Screening (HTS) Spotter for 3D Tumor Spheroid Formation
por: Jeong, Mi-Hyeon, et al.
Publicado: (2023)

Spheroid arrays for high-throughput single-cell analysis of spatial patterns and biomarker expression in 3D
por: Ivanov, Delyan P., et al.
Publicado: (2017)

A novel 3D pillar/well array platform using patient-derived head and neck tumor to predict the individual radioresponse
por: Lee, Dong Woo, et al.
Publicado: (2022)

Vascularization of iNSC spheroid in a 3D spheroid‐on‐a‐chip platform enhances neural maturation
por: Shin, Nari, et al.
Publicado: (2021)

The Microwell-mesh: A high-throughput 3D prostate cancer spheroid and drug-testing platform
por: Mosaad, E. O., et al.
Publicado: (2018)

Fucoidan-Manganese Dioxide Nanoparticles Potentiate Radiation Therapy by Co-Targeting Tumor Hypoxia and Angiogenesis
por: Shin, Sung-Won, et al.
Publicado: (2018)

A Highly Reproducible Micro U‐Well Array Plate Facilitating High‐Throughput Tumor Spheroid Culture and Drug Assessment
por: Wu, Kuang‐Wei, et al.
Publicado: (2020)

Electromechanical Characteristics by a Vertical Flip of C(70) Fullerene Prolate Spheroid in a Single-Electron Transistor: Hybrid Density Functional Methods
por: Choi, Jong Woan, et al.
Publicado: (2021)

Cell spheroids culture array with modifiable chemical gradients
por: Yang, Panhui, et al.
Publicado: (2023)

High-Throughput Screening of Acyl-CoA Thioesterase I Mutants Using a Fluid Array Platform
por: Lim, Ji Won, et al.
Publicado: (2019)

Oxygenated Theonellastrols: Interpretation of Unusual Chemical Behaviors Using Quantum Mechanical Calculations and Stereochemical Reassignment of 7α-Hydroxytheonellasterol
por: Shin, A-Young, et al.
Publicado: (2020)

3D tumor spheroid microarray for high-throughput, high-content natural killer cell-mediated cytotoxicity
por: Gopal, Sneha, et al.
Publicado: (2021)

Inversion Genotyping in the Anopheles gambiae Complex Using High-Throughput Array and Sequencing Platforms
por: Love, R. Rebecca, et al.
Publicado: (2020)

Reconfigurable Microfluidic Magnetic Valve Arrays: Towards a Radiotherapy-Compatible Spheroid Culture Platform for the Combinatorial Screening of Cancer Therapies
por: Brunet, Alexandre R., et al.
Publicado: (2017)

High‐throughput screening in colorectal cancer tissue‐originated spheroids
por: Kondo, Jumpei, et al.
Publicado: (2018)

High-throughput cell and spheroid mechanics in virtual fluidic channels
por: Panhwar, Muzaffar H., et al.
Publicado: (2020)

A High-Throughput and Uniform Amplification Method for Cell Spheroids
por: Liu, Liyuan, et al.
Publicado: (2022)

Two Decades of Arrayed Imaging Reflectometry for Sensitive, High-Throughput Biosensing
por: Kosoy, Gabrielle, et al.
Publicado: (2023)

Heterotypic tumor spheroids: a platform for nanomedicine evaluation
por: Vakhshiteh, Faezeh, et al.
Publicado: (2023)

Tumor Spheroids as an In Vitro Model for Determining the Therapeutic Response to Proton Beam Radiotherapy and Thermally Sensitive Nanocarriers
por: Senavirathna, Lakmini K., et al.
Publicado: (2013)

Deciphering the underlying mechanism of liver diseases through utilization of multicellular hepatic spheroid models
por: Kim, Sanghwa, et al.
Publicado: (2023)

Rapid generation of homogenous tumor spheroid microtissues in a scaffold-free platform for high-throughput screening of a novel combination nanomedicine
por: Abolhassani, Hossein, et al.
Publicado: (2023)

Shift of EMT gradient in 3D spheroid MSCs for activation of mesenchymal niche function
por: Jeon, Sohee, et al.
Publicado: (2017)

Multiplexing Spheroid Volume, Resazurin and Acid Phosphatase Viability Assays for High-Throughput Screening of Tumour Spheroids and Stem Cell Neurospheres
por: Ivanov, Delyan P., et al.
Publicado: (2014)

High-throughput Image Analysis of Tumor Spheroids: A User-friendly Software Application to Measure the Size of Spheroids Automatically and Accurately
por: Chen, Wenjin, et al.
Publicado: (2014)

Targeting Na-H exchanger 1 overcomes nuclear factor kappa B-mediated tumor resistance to radiotherapy
por: Son, Arang, et al.
Publicado: (2022)

The first private-hospital based proton therapy center in Korea; status of the Proton Therapy Center at Samsung Medical Center
por: Chung, Kwangzoo, et al.
Publicado: (2015)

A Highly Reproducible Micro U‐Well Array Plate Facilitating High‐Throughput Tumor Spheroid Culture and Drug Assessment (Global Challenges 2/2021)
por: Wu, Kuang‐Wei, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_0c5e26vacmr9cokccstf8h2dns