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Symptomatic SARS-CoV-2 Infection with Ageusia after Two mRNA Vaccine Doses
To raise awareness about preventive measures in COVID-19 pandemic, even though fully vaccinated. Although recent trials showed high efficacy of vaccines in preventing symptomatic infections, there are some individuals experiencing symptomatic SARS-CoV-2 infection. In this case report, a fully vaccin...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775558/ https://www.ncbi.nlm.nih.gov/pubmed/35055707 http://dx.doi.org/10.3390/ijerph19020886 |
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author | Caponio, Vito Carlo Alberto Lipsi, Maria Rosaria Fortunato, Francesca Arena, Fabio Lo Muzio, Lorenzo |
author_facet | Caponio, Vito Carlo Alberto Lipsi, Maria Rosaria Fortunato, Francesca Arena, Fabio Lo Muzio, Lorenzo |
author_sort | Caponio, Vito Carlo Alberto |
collection | PubMed |
description | To raise awareness about preventive measures in COVID-19 pandemic, even though fully vaccinated. Although recent trials showed high efficacy of vaccines in preventing symptomatic infections, there are some individuals experiencing symptomatic SARS-CoV-2 infection. In this case report, a fully vaccinated young dental practitioner experienced symptomatic SARS-CoV-2 infection 55 days postvaccination with BNT162b2 Pfizer vaccine with evident ageusia. Diagnostic swabs were performed and used for viral genome sequencing. The patient fully recovered 15 days after diagnosis. Loss of smell and taste, together with nasal congestion were the main reported symptoms. The use of personal protective equipment prevented spread of infection in patients and co-workers. With the increase of people being fully vaccinated, it is still necessary to follow infection preventive protocols by correctly applying personal protective equipment. Although high efficacy has been proved, some individuals may still be vulnerable to symptomatic infection and new guidelines and markers should be adopted and investigated to find out patients for whom vaccination may not determine full immunization. |
format | Online Article Text |
id | pubmed-8775558 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87755582022-01-21 Symptomatic SARS-CoV-2 Infection with Ageusia after Two mRNA Vaccine Doses Caponio, Vito Carlo Alberto Lipsi, Maria Rosaria Fortunato, Francesca Arena, Fabio Lo Muzio, Lorenzo Int J Environ Res Public Health Case Report To raise awareness about preventive measures in COVID-19 pandemic, even though fully vaccinated. Although recent trials showed high efficacy of vaccines in preventing symptomatic infections, there are some individuals experiencing symptomatic SARS-CoV-2 infection. In this case report, a fully vaccinated young dental practitioner experienced symptomatic SARS-CoV-2 infection 55 days postvaccination with BNT162b2 Pfizer vaccine with evident ageusia. Diagnostic swabs were performed and used for viral genome sequencing. The patient fully recovered 15 days after diagnosis. Loss of smell and taste, together with nasal congestion were the main reported symptoms. The use of personal protective equipment prevented spread of infection in patients and co-workers. With the increase of people being fully vaccinated, it is still necessary to follow infection preventive protocols by correctly applying personal protective equipment. Although high efficacy has been proved, some individuals may still be vulnerable to symptomatic infection and new guidelines and markers should be adopted and investigated to find out patients for whom vaccination may not determine full immunization. MDPI 2022-01-13 /pmc/articles/PMC8775558/ /pubmed/35055707 http://dx.doi.org/10.3390/ijerph19020886 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Caponio, Vito Carlo Alberto Lipsi, Maria Rosaria Fortunato, Francesca Arena, Fabio Lo Muzio, Lorenzo Symptomatic SARS-CoV-2 Infection with Ageusia after Two mRNA Vaccine Doses |
title | Symptomatic SARS-CoV-2 Infection with Ageusia after Two mRNA Vaccine Doses |
title_full | Symptomatic SARS-CoV-2 Infection with Ageusia after Two mRNA Vaccine Doses |
title_fullStr | Symptomatic SARS-CoV-2 Infection with Ageusia after Two mRNA Vaccine Doses |
title_full_unstemmed | Symptomatic SARS-CoV-2 Infection with Ageusia after Two mRNA Vaccine Doses |
title_short | Symptomatic SARS-CoV-2 Infection with Ageusia after Two mRNA Vaccine Doses |
title_sort | symptomatic sars-cov-2 infection with ageusia after two mrna vaccine doses |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775558/ https://www.ncbi.nlm.nih.gov/pubmed/35055707 http://dx.doi.org/10.3390/ijerph19020886 |
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