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Symptomatic SARS-CoV-2 Infection with Ageusia after Two mRNA Vaccine Doses

To raise awareness about preventive measures in COVID-19 pandemic, even though fully vaccinated. Although recent trials showed high efficacy of vaccines in preventing symptomatic infections, there are some individuals experiencing symptomatic SARS-CoV-2 infection. In this case report, a fully vaccin...

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Autores principales: Caponio, Vito Carlo Alberto, Lipsi, Maria Rosaria, Fortunato, Francesca, Arena, Fabio, Lo Muzio, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775558/
https://www.ncbi.nlm.nih.gov/pubmed/35055707
http://dx.doi.org/10.3390/ijerph19020886
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author Caponio, Vito Carlo Alberto
Lipsi, Maria Rosaria
Fortunato, Francesca
Arena, Fabio
Lo Muzio, Lorenzo
author_facet Caponio, Vito Carlo Alberto
Lipsi, Maria Rosaria
Fortunato, Francesca
Arena, Fabio
Lo Muzio, Lorenzo
author_sort Caponio, Vito Carlo Alberto
collection PubMed
description To raise awareness about preventive measures in COVID-19 pandemic, even though fully vaccinated. Although recent trials showed high efficacy of vaccines in preventing symptomatic infections, there are some individuals experiencing symptomatic SARS-CoV-2 infection. In this case report, a fully vaccinated young dental practitioner experienced symptomatic SARS-CoV-2 infection 55 days postvaccination with BNT162b2 Pfizer vaccine with evident ageusia. Diagnostic swabs were performed and used for viral genome sequencing. The patient fully recovered 15 days after diagnosis. Loss of smell and taste, together with nasal congestion were the main reported symptoms. The use of personal protective equipment prevented spread of infection in patients and co-workers. With the increase of people being fully vaccinated, it is still necessary to follow infection preventive protocols by correctly applying personal protective equipment. Although high efficacy has been proved, some individuals may still be vulnerable to symptomatic infection and new guidelines and markers should be adopted and investigated to find out patients for whom vaccination may not determine full immunization.
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spelling pubmed-87755582022-01-21 Symptomatic SARS-CoV-2 Infection with Ageusia after Two mRNA Vaccine Doses Caponio, Vito Carlo Alberto Lipsi, Maria Rosaria Fortunato, Francesca Arena, Fabio Lo Muzio, Lorenzo Int J Environ Res Public Health Case Report To raise awareness about preventive measures in COVID-19 pandemic, even though fully vaccinated. Although recent trials showed high efficacy of vaccines in preventing symptomatic infections, there are some individuals experiencing symptomatic SARS-CoV-2 infection. In this case report, a fully vaccinated young dental practitioner experienced symptomatic SARS-CoV-2 infection 55 days postvaccination with BNT162b2 Pfizer vaccine with evident ageusia. Diagnostic swabs were performed and used for viral genome sequencing. The patient fully recovered 15 days after diagnosis. Loss of smell and taste, together with nasal congestion were the main reported symptoms. The use of personal protective equipment prevented spread of infection in patients and co-workers. With the increase of people being fully vaccinated, it is still necessary to follow infection preventive protocols by correctly applying personal protective equipment. Although high efficacy has been proved, some individuals may still be vulnerable to symptomatic infection and new guidelines and markers should be adopted and investigated to find out patients for whom vaccination may not determine full immunization. MDPI 2022-01-13 /pmc/articles/PMC8775558/ /pubmed/35055707 http://dx.doi.org/10.3390/ijerph19020886 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Caponio, Vito Carlo Alberto
Lipsi, Maria Rosaria
Fortunato, Francesca
Arena, Fabio
Lo Muzio, Lorenzo
Symptomatic SARS-CoV-2 Infection with Ageusia after Two mRNA Vaccine Doses
title Symptomatic SARS-CoV-2 Infection with Ageusia after Two mRNA Vaccine Doses
title_full Symptomatic SARS-CoV-2 Infection with Ageusia after Two mRNA Vaccine Doses
title_fullStr Symptomatic SARS-CoV-2 Infection with Ageusia after Two mRNA Vaccine Doses
title_full_unstemmed Symptomatic SARS-CoV-2 Infection with Ageusia after Two mRNA Vaccine Doses
title_short Symptomatic SARS-CoV-2 Infection with Ageusia after Two mRNA Vaccine Doses
title_sort symptomatic sars-cov-2 infection with ageusia after two mrna vaccine doses
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775558/
https://www.ncbi.nlm.nih.gov/pubmed/35055707
http://dx.doi.org/10.3390/ijerph19020886
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