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Functional In Vitro Assessment of VEGFA/NOTCH2 Signaling Pathway and pRB Proteasomal Degradation and the Clinical Relevance of Mucolipin TRPML2 Overexpression in Glioblastoma Patients

Glioblastoma (GBM) is the most malignant glioma with an extremely poor prognosis. It is characterized by high vascularization and its growth depends on the formation of new blood vessels. We have previously demonstrated that TRPML2 mucolipin channel expression increases with the glioma pathological...

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Detalles Bibliográficos
Autores principales:	Santoni, Giorgio, Amantini, Consuelo, Nabissi, Massimo, Arcella, Antonietta, Maggi, Federica, Santoni, Matteo, Morelli, Maria Beatrice
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775570/ https://www.ncbi.nlm.nih.gov/pubmed/35054871 http://dx.doi.org/10.3390/ijms23020688

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