Nanomechanical Atomic Force Microscopy to Probe Cellular Microplastics Uptake and Distribution

The concerns regarding microplastics and nanoplastics pollution stimulate studies on the uptake and biodistribution of these emerging pollutants in vitro. Atomic force microscopy in nanomechanical PeakForce Tapping mode was used here to visualise the uptake and distribution of polystyrene spherical...

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Autores principales: Akhatova, Farida, Ishmukhametov, Ilnur, Fakhrullina, Gölnur, Fakhrullin, Rawil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775627/
https://www.ncbi.nlm.nih.gov/pubmed/35054990
http://dx.doi.org/10.3390/ijms23020806
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author Akhatova, Farida
Ishmukhametov, Ilnur
Fakhrullina, Gölnur
Fakhrullin, Rawil
author_facet Akhatova, Farida
Ishmukhametov, Ilnur
Fakhrullina, Gölnur
Fakhrullin, Rawil
author_sort Akhatova, Farida
collection PubMed
description The concerns regarding microplastics and nanoplastics pollution stimulate studies on the uptake and biodistribution of these emerging pollutants in vitro. Atomic force microscopy in nanomechanical PeakForce Tapping mode was used here to visualise the uptake and distribution of polystyrene spherical microplastics in human skin fibroblast. Particles down to 500 nm were imaged in whole fixed cells, the nanomechanical characterization allowed for differentiation between internalized and surface attached plastics. This study opens new avenues in microplastics toxicity research.
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spelling pubmed-87756272022-01-21 Nanomechanical Atomic Force Microscopy to Probe Cellular Microplastics Uptake and Distribution Akhatova, Farida Ishmukhametov, Ilnur Fakhrullina, Gölnur Fakhrullin, Rawil Int J Mol Sci Communication The concerns regarding microplastics and nanoplastics pollution stimulate studies on the uptake and biodistribution of these emerging pollutants in vitro. Atomic force microscopy in nanomechanical PeakForce Tapping mode was used here to visualise the uptake and distribution of polystyrene spherical microplastics in human skin fibroblast. Particles down to 500 nm were imaged in whole fixed cells, the nanomechanical characterization allowed for differentiation between internalized and surface attached plastics. This study opens new avenues in microplastics toxicity research. MDPI 2022-01-12 /pmc/articles/PMC8775627/ /pubmed/35054990 http://dx.doi.org/10.3390/ijms23020806 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Akhatova, Farida
Ishmukhametov, Ilnur
Fakhrullina, Gölnur
Fakhrullin, Rawil
Nanomechanical Atomic Force Microscopy to Probe Cellular Microplastics Uptake and Distribution
title Nanomechanical Atomic Force Microscopy to Probe Cellular Microplastics Uptake and Distribution
title_full Nanomechanical Atomic Force Microscopy to Probe Cellular Microplastics Uptake and Distribution
title_fullStr Nanomechanical Atomic Force Microscopy to Probe Cellular Microplastics Uptake and Distribution
title_full_unstemmed Nanomechanical Atomic Force Microscopy to Probe Cellular Microplastics Uptake and Distribution
title_short Nanomechanical Atomic Force Microscopy to Probe Cellular Microplastics Uptake and Distribution
title_sort nanomechanical atomic force microscopy to probe cellular microplastics uptake and distribution
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775627/
https://www.ncbi.nlm.nih.gov/pubmed/35054990
http://dx.doi.org/10.3390/ijms23020806
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AT fakhrullinagolnur nanomechanicalatomicforcemicroscopytoprobecellularmicroplasticsuptakeanddistribution
AT fakhrullinrawil nanomechanicalatomicforcemicroscopytoprobecellularmicroplasticsuptakeanddistribution

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