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Tk-deleted Pseudorabies Virus Retains High Pathogenicity in Rats

INTRODUCTION: The pseudorabies virus (PRV) gene encoding thymidine kinase (tk) is an important virulence-associated factor. Attenuation of PRV in susceptible animals is a frequent result of tk deletion. The aim of the study was to assess the pathogenicity of tk-deleted PRV in rats. MATERIAL AND METH...

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Detalles Bibliográficos
Autores principales:	Zhang, Lirong, Ruan, Keyue, Sang, Guoju, Xu, Zhaoyang, Tong, Wu, Yu, Hai, Shan, Tongling, Gao, Fei, Li, Liwei, Kong, Ning, Tong, Guangzhi, Zheng, Hao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Sciendo 2021
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775734/ https://www.ncbi.nlm.nih.gov/pubmed/35111992 http://dx.doi.org/10.2478/jvetres-2021-0056

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