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The Role of GRP and MGP in the Development of Non-Hemorrhagic VKCFD1 Phenotypes

Vitamin K dependent coagulation factor deficiency type 1 (VKCFD1) is a rare hereditary bleeding disorder caused by mutations in γ-Glutamyl carboxylase (GGCX) gene. The GGCX enzyme catalyzes the γ-carboxylation of 15 different vitamin K dependent (VKD) proteins, which have function in blood coagulati...

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Detalles Bibliográficos
Autores principales:	Ghosh, Suvoshree, Oldenburg, Johannes, Czogalla-Nitsche, Katrin J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775833/ https://www.ncbi.nlm.nih.gov/pubmed/35054981 http://dx.doi.org/10.3390/ijms23020798

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