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Pharmacy-Based Opportunistic Atrial Fibrillation Screening at a Community Level: A Real-Life Study

Purpose: Opportunistic pharmacy-based screening of atrial fibrillation (AF) appears effective, but the proportion of detected citizens is unknown. The aim of our real-life study was to determine rates of screening in a community population according to age group and gender. Methods: We conducted fou...

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Autores principales: Olindo, Stephane, Renou, Pauline, Martial, François, Heyvang, Nathalie, Milan, Lea, Ledure, Sylvain, Rouanet, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775917/
https://www.ncbi.nlm.nih.gov/pubmed/35052253
http://dx.doi.org/10.3390/healthcare10010090
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author Olindo, Stephane
Renou, Pauline
Martial, François
Heyvang, Nathalie
Milan, Lea
Ledure, Sylvain
Rouanet, François
author_facet Olindo, Stephane
Renou, Pauline
Martial, François
Heyvang, Nathalie
Milan, Lea
Ledure, Sylvain
Rouanet, François
author_sort Olindo, Stephane
collection PubMed
description Purpose: Opportunistic pharmacy-based screening of atrial fibrillation (AF) appears effective, but the proportion of detected citizens is unknown. The aim of our real-life study was to determine rates of screening in a community population according to age group and gender. Methods: We conducted four community campaigns of pharmacy-based single-time point AF screening that involved individuals ≥65 years. We used a single-lead and hand-held device MyDiagnostick (6229 EV Maastricht, The Netherlands) that generates a 60-s ECG trace. All pharmacies of the communities (n = 54) were involved. Rates of screening were assessed on the base of the French National Institute for Statistics and Economic Studies data and were expressed as percentage and 95% Confidence interval (CI). Results: We screened 4208 individuals (Mean age, 74.2 ± 6.6 years; females, 60.2%). The screening rate in citizens aged ≥65 years was 17.2% (16.6–17.7), and higher in females than in males (17.9% [17.3–18.6] versus 16.0 [15.3–16.8], p < 0.001). The 70–74 age group showed the highest rate (25.7% [24.4–27]) compared to other groups. After 74 years, screening rates decreased steadily with age and dropped to 4.8% [3.8–6.1] in very elderly (≥90). Among the 188 (4.47%) positive screening, 117 (2.78%) showed an AF that was unknown in 53 (1.26%). Increasing age (OR: 1.05 [1.00–1.09], p = 0.04), male sex (OR: 4.30 [2.33–7.92], p < 0.0001) and high CHA2DS2-Vasc (OR: 1.59 [1.21–2.09], p = 0.0008) were independent predictors of unknown AF. Conclusion: Single-lead AF detection performed in community pharmacies result in screening one in six elderly citizens. Although male sex and elderly predicted unknown AF diagnosis, they were less involved in such designed campaigns.
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spelling pubmed-87759172022-01-21 Pharmacy-Based Opportunistic Atrial Fibrillation Screening at a Community Level: A Real-Life Study Olindo, Stephane Renou, Pauline Martial, François Heyvang, Nathalie Milan, Lea Ledure, Sylvain Rouanet, François Healthcare (Basel) Article Purpose: Opportunistic pharmacy-based screening of atrial fibrillation (AF) appears effective, but the proportion of detected citizens is unknown. The aim of our real-life study was to determine rates of screening in a community population according to age group and gender. Methods: We conducted four community campaigns of pharmacy-based single-time point AF screening that involved individuals ≥65 years. We used a single-lead and hand-held device MyDiagnostick (6229 EV Maastricht, The Netherlands) that generates a 60-s ECG trace. All pharmacies of the communities (n = 54) were involved. Rates of screening were assessed on the base of the French National Institute for Statistics and Economic Studies data and were expressed as percentage and 95% Confidence interval (CI). Results: We screened 4208 individuals (Mean age, 74.2 ± 6.6 years; females, 60.2%). The screening rate in citizens aged ≥65 years was 17.2% (16.6–17.7), and higher in females than in males (17.9% [17.3–18.6] versus 16.0 [15.3–16.8], p < 0.001). The 70–74 age group showed the highest rate (25.7% [24.4–27]) compared to other groups. After 74 years, screening rates decreased steadily with age and dropped to 4.8% [3.8–6.1] in very elderly (≥90). Among the 188 (4.47%) positive screening, 117 (2.78%) showed an AF that was unknown in 53 (1.26%). Increasing age (OR: 1.05 [1.00–1.09], p = 0.04), male sex (OR: 4.30 [2.33–7.92], p < 0.0001) and high CHA2DS2-Vasc (OR: 1.59 [1.21–2.09], p = 0.0008) were independent predictors of unknown AF. Conclusion: Single-lead AF detection performed in community pharmacies result in screening one in six elderly citizens. Although male sex and elderly predicted unknown AF diagnosis, they were less involved in such designed campaigns. MDPI 2022-01-04 /pmc/articles/PMC8775917/ /pubmed/35052253 http://dx.doi.org/10.3390/healthcare10010090 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Olindo, Stephane
Renou, Pauline
Martial, François
Heyvang, Nathalie
Milan, Lea
Ledure, Sylvain
Rouanet, François
Pharmacy-Based Opportunistic Atrial Fibrillation Screening at a Community Level: A Real-Life Study
title Pharmacy-Based Opportunistic Atrial Fibrillation Screening at a Community Level: A Real-Life Study
title_full Pharmacy-Based Opportunistic Atrial Fibrillation Screening at a Community Level: A Real-Life Study
title_fullStr Pharmacy-Based Opportunistic Atrial Fibrillation Screening at a Community Level: A Real-Life Study
title_full_unstemmed Pharmacy-Based Opportunistic Atrial Fibrillation Screening at a Community Level: A Real-Life Study
title_short Pharmacy-Based Opportunistic Atrial Fibrillation Screening at a Community Level: A Real-Life Study
title_sort pharmacy-based opportunistic atrial fibrillation screening at a community level: a real-life study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775917/
https://www.ncbi.nlm.nih.gov/pubmed/35052253
http://dx.doi.org/10.3390/healthcare10010090
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