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Pharmacy-Based Opportunistic Atrial Fibrillation Screening at a Community Level: A Real-Life Study
Purpose: Opportunistic pharmacy-based screening of atrial fibrillation (AF) appears effective, but the proportion of detected citizens is unknown. The aim of our real-life study was to determine rates of screening in a community population according to age group and gender. Methods: We conducted fou...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775917/ https://www.ncbi.nlm.nih.gov/pubmed/35052253 http://dx.doi.org/10.3390/healthcare10010090 |
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author | Olindo, Stephane Renou, Pauline Martial, François Heyvang, Nathalie Milan, Lea Ledure, Sylvain Rouanet, François |
author_facet | Olindo, Stephane Renou, Pauline Martial, François Heyvang, Nathalie Milan, Lea Ledure, Sylvain Rouanet, François |
author_sort | Olindo, Stephane |
collection | PubMed |
description | Purpose: Opportunistic pharmacy-based screening of atrial fibrillation (AF) appears effective, but the proportion of detected citizens is unknown. The aim of our real-life study was to determine rates of screening in a community population according to age group and gender. Methods: We conducted four community campaigns of pharmacy-based single-time point AF screening that involved individuals ≥65 years. We used a single-lead and hand-held device MyDiagnostick (6229 EV Maastricht, The Netherlands) that generates a 60-s ECG trace. All pharmacies of the communities (n = 54) were involved. Rates of screening were assessed on the base of the French National Institute for Statistics and Economic Studies data and were expressed as percentage and 95% Confidence interval (CI). Results: We screened 4208 individuals (Mean age, 74.2 ± 6.6 years; females, 60.2%). The screening rate in citizens aged ≥65 years was 17.2% (16.6–17.7), and higher in females than in males (17.9% [17.3–18.6] versus 16.0 [15.3–16.8], p < 0.001). The 70–74 age group showed the highest rate (25.7% [24.4–27]) compared to other groups. After 74 years, screening rates decreased steadily with age and dropped to 4.8% [3.8–6.1] in very elderly (≥90). Among the 188 (4.47%) positive screening, 117 (2.78%) showed an AF that was unknown in 53 (1.26%). Increasing age (OR: 1.05 [1.00–1.09], p = 0.04), male sex (OR: 4.30 [2.33–7.92], p < 0.0001) and high CHA2DS2-Vasc (OR: 1.59 [1.21–2.09], p = 0.0008) were independent predictors of unknown AF. Conclusion: Single-lead AF detection performed in community pharmacies result in screening one in six elderly citizens. Although male sex and elderly predicted unknown AF diagnosis, they were less involved in such designed campaigns. |
format | Online Article Text |
id | pubmed-8775917 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87759172022-01-21 Pharmacy-Based Opportunistic Atrial Fibrillation Screening at a Community Level: A Real-Life Study Olindo, Stephane Renou, Pauline Martial, François Heyvang, Nathalie Milan, Lea Ledure, Sylvain Rouanet, François Healthcare (Basel) Article Purpose: Opportunistic pharmacy-based screening of atrial fibrillation (AF) appears effective, but the proportion of detected citizens is unknown. The aim of our real-life study was to determine rates of screening in a community population according to age group and gender. Methods: We conducted four community campaigns of pharmacy-based single-time point AF screening that involved individuals ≥65 years. We used a single-lead and hand-held device MyDiagnostick (6229 EV Maastricht, The Netherlands) that generates a 60-s ECG trace. All pharmacies of the communities (n = 54) were involved. Rates of screening were assessed on the base of the French National Institute for Statistics and Economic Studies data and were expressed as percentage and 95% Confidence interval (CI). Results: We screened 4208 individuals (Mean age, 74.2 ± 6.6 years; females, 60.2%). The screening rate in citizens aged ≥65 years was 17.2% (16.6–17.7), and higher in females than in males (17.9% [17.3–18.6] versus 16.0 [15.3–16.8], p < 0.001). The 70–74 age group showed the highest rate (25.7% [24.4–27]) compared to other groups. After 74 years, screening rates decreased steadily with age and dropped to 4.8% [3.8–6.1] in very elderly (≥90). Among the 188 (4.47%) positive screening, 117 (2.78%) showed an AF that was unknown in 53 (1.26%). Increasing age (OR: 1.05 [1.00–1.09], p = 0.04), male sex (OR: 4.30 [2.33–7.92], p < 0.0001) and high CHA2DS2-Vasc (OR: 1.59 [1.21–2.09], p = 0.0008) were independent predictors of unknown AF. Conclusion: Single-lead AF detection performed in community pharmacies result in screening one in six elderly citizens. Although male sex and elderly predicted unknown AF diagnosis, they were less involved in such designed campaigns. MDPI 2022-01-04 /pmc/articles/PMC8775917/ /pubmed/35052253 http://dx.doi.org/10.3390/healthcare10010090 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Olindo, Stephane Renou, Pauline Martial, François Heyvang, Nathalie Milan, Lea Ledure, Sylvain Rouanet, François Pharmacy-Based Opportunistic Atrial Fibrillation Screening at a Community Level: A Real-Life Study |
title | Pharmacy-Based Opportunistic Atrial Fibrillation Screening at a Community Level: A Real-Life Study |
title_full | Pharmacy-Based Opportunistic Atrial Fibrillation Screening at a Community Level: A Real-Life Study |
title_fullStr | Pharmacy-Based Opportunistic Atrial Fibrillation Screening at a Community Level: A Real-Life Study |
title_full_unstemmed | Pharmacy-Based Opportunistic Atrial Fibrillation Screening at a Community Level: A Real-Life Study |
title_short | Pharmacy-Based Opportunistic Atrial Fibrillation Screening at a Community Level: A Real-Life Study |
title_sort | pharmacy-based opportunistic atrial fibrillation screening at a community level: a real-life study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775917/ https://www.ncbi.nlm.nih.gov/pubmed/35052253 http://dx.doi.org/10.3390/healthcare10010090 |
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