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Lipoprotein Profile in Populations from Regions of the Russian Federation: ESSE-RF Study
This study aimed to describe the dyslipidemia prevalence and pattern among adult populations from different regions (n = 13) of the Russian Federation (RF). Randomly selected samples (n = 22,258, aged 25–64) were studied according to the ESSE-RF protocol. Lipoprotein parameters were estimated by rou...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775951/ https://www.ncbi.nlm.nih.gov/pubmed/35055754 http://dx.doi.org/10.3390/ijerph19020931 |
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author | Metelskaya, Victoria A. Shalnova, Svetlana A. Yarovaya, Elena B. Kutsenko, Vladimir A. Boytsov, Sergey A. Shlyakhto, Eugeny V. Drapkina, Oxana M. |
author_facet | Metelskaya, Victoria A. Shalnova, Svetlana A. Yarovaya, Elena B. Kutsenko, Vladimir A. Boytsov, Sergey A. Shlyakhto, Eugeny V. Drapkina, Oxana M. |
author_sort | Metelskaya, Victoria A. |
collection | PubMed |
description | This study aimed to describe the dyslipidemia prevalence and pattern among adult populations from different regions (n = 13) of the Russian Federation (RF). Randomly selected samples (n = 22,258, aged 25–64) were studied according to the ESSE-RF protocol. Lipoprotein parameters were estimated by routine methods. Statistical analyses were performed using R software (v.3.5.1). The overall dyslipidemia prevalence was 76.1% (76.9/75.3% for men/women). In women, total cholesterol (TC) and low-density lipoprotein (LDL)-C levels gradually increased with age (from 4.72 to 5.93 and from 2.76 to 3.79 mmol/L, respectively); in men, they reached a maximum by 45–54 (5.55 and 3.55 mmol/L, respectively) and then decreased. No differences in high-density lipoprotein (HDL)-C in men of different ages were found, but slight decreases in HDL-C and apo AI were observed in women by 55–64 years. No pronounced associations between education and lipid levels in men were observed; higher-educated women showed significantly better lipoprotein profiles. Similar associations between lipids and income level were detected. Women from rural areas had higher TC and triglycerides than urban residents. Regardless of sex, rural residents had higher HDL-C and apo AI, and reduced apo B/apo AI. Conclusion: Information on the peculiarities of dyslipidemia prevalence and lipoprotein profile depending on sex, age, residential place, and socioeconomic status is useful for assessing the global ASCVD risk, and for risk modeling based on national data. |
format | Online Article Text |
id | pubmed-8775951 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87759512022-01-21 Lipoprotein Profile in Populations from Regions of the Russian Federation: ESSE-RF Study Metelskaya, Victoria A. Shalnova, Svetlana A. Yarovaya, Elena B. Kutsenko, Vladimir A. Boytsov, Sergey A. Shlyakhto, Eugeny V. Drapkina, Oxana M. Int J Environ Res Public Health Article This study aimed to describe the dyslipidemia prevalence and pattern among adult populations from different regions (n = 13) of the Russian Federation (RF). Randomly selected samples (n = 22,258, aged 25–64) were studied according to the ESSE-RF protocol. Lipoprotein parameters were estimated by routine methods. Statistical analyses were performed using R software (v.3.5.1). The overall dyslipidemia prevalence was 76.1% (76.9/75.3% for men/women). In women, total cholesterol (TC) and low-density lipoprotein (LDL)-C levels gradually increased with age (from 4.72 to 5.93 and from 2.76 to 3.79 mmol/L, respectively); in men, they reached a maximum by 45–54 (5.55 and 3.55 mmol/L, respectively) and then decreased. No differences in high-density lipoprotein (HDL)-C in men of different ages were found, but slight decreases in HDL-C and apo AI were observed in women by 55–64 years. No pronounced associations between education and lipid levels in men were observed; higher-educated women showed significantly better lipoprotein profiles. Similar associations between lipids and income level were detected. Women from rural areas had higher TC and triglycerides than urban residents. Regardless of sex, rural residents had higher HDL-C and apo AI, and reduced apo B/apo AI. Conclusion: Information on the peculiarities of dyslipidemia prevalence and lipoprotein profile depending on sex, age, residential place, and socioeconomic status is useful for assessing the global ASCVD risk, and for risk modeling based on national data. MDPI 2022-01-14 /pmc/articles/PMC8775951/ /pubmed/35055754 http://dx.doi.org/10.3390/ijerph19020931 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Metelskaya, Victoria A. Shalnova, Svetlana A. Yarovaya, Elena B. Kutsenko, Vladimir A. Boytsov, Sergey A. Shlyakhto, Eugeny V. Drapkina, Oxana M. Lipoprotein Profile in Populations from Regions of the Russian Federation: ESSE-RF Study |
title | Lipoprotein Profile in Populations from Regions of the Russian Federation: ESSE-RF Study |
title_full | Lipoprotein Profile in Populations from Regions of the Russian Federation: ESSE-RF Study |
title_fullStr | Lipoprotein Profile in Populations from Regions of the Russian Federation: ESSE-RF Study |
title_full_unstemmed | Lipoprotein Profile in Populations from Regions of the Russian Federation: ESSE-RF Study |
title_short | Lipoprotein Profile in Populations from Regions of the Russian Federation: ESSE-RF Study |
title_sort | lipoprotein profile in populations from regions of the russian federation: esse-rf study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8775951/ https://www.ncbi.nlm.nih.gov/pubmed/35055754 http://dx.doi.org/10.3390/ijerph19020931 |
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