Dual Blockade of TNF and IL-17A Inhibits Inflammation and Structural Damage in a Rat Model of Spondyloarthritis

The tumor necrosis factor (TNF) and IL-23/IL-17 axes are the main therapeutic targets in spondyloarthritis. Despite the clinical efficacy of blocking either pathway, monotherapy does not induce remission in all patients and its effect on new bone formation remains unclear. We aimed to study the effe...

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Detalles Bibliográficos
Autores principales: Hammoura, Ihsan, Fiechter, Renee H., Bryant, Shaughn H., Westmoreland, Susan, Kingsbury, Gillian, Waegell, Wendy, Tas, Sander W., Baeten, Dominique L., van de Sande, Marleen G. H., van Tok, Melissa N., van Duivenvoorde, Leonie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776047/
https://www.ncbi.nlm.nih.gov/pubmed/35055042
http://dx.doi.org/10.3390/ijms23020859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776047/
https://www.ncbi.nlm.nih.gov/pubmed/35055042
http://dx.doi.org/10.3390/ijms23020859

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