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Knowledge and Use of Novel Psychoactive Substances in an Italian Sample with Substance Use Disorders
This study aims to determine prevalence and frequency of use of novel psychoactive substances (NPS) and to identify the factors associated with NPS use in an Italian sample of patients diagnosed with substance use disorder (SUD). Prevalence and correlates of NPS knowledge and use were assessed in 18...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776073/ https://www.ncbi.nlm.nih.gov/pubmed/35055743 http://dx.doi.org/10.3390/ijerph19020915 |
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author | Dal Farra, Deborah Valdesalici, Alice Zecchinato, Giancarlo De Sandre, Alfio Saccon, Diego Simonato, Pierluigi Corazza, Ornella Martinotti, Giovanni Smith, Andrew L. Solmi, Marco |
author_facet | Dal Farra, Deborah Valdesalici, Alice Zecchinato, Giancarlo De Sandre, Alfio Saccon, Diego Simonato, Pierluigi Corazza, Ornella Martinotti, Giovanni Smith, Andrew L. Solmi, Marco |
author_sort | Dal Farra, Deborah |
collection | PubMed |
description | This study aims to determine prevalence and frequency of use of novel psychoactive substances (NPS) and to identify the factors associated with NPS use in an Italian sample of patients diagnosed with substance use disorder (SUD). Prevalence and correlates of NPS knowledge and use were assessed in 185 patients with SUD in three addiction services (Padova, Belluno, Feltre) in the Veneto region with an ad-hoc designed survey. Two thirds of the samples reported knowing NPS and one third reported using them. NPS were considered by them less dangerous than “regular” substances of abuse (t = 6.06 mean 0.78, p < 0.001). Factors associated with NPS use were youth (OR = 4.81; p < 0.001), studentship (OR = 4.99; p = 0.004), subsequent mental disorders diagnosis (OR = 2.49; p = 0.027), suicide attempt history (OR = 11.67; p < 0.001), home detention (OR = 2.30; p = 0.040), residential care (OR = 5.66; p = 0.002), and polysubstance abuse (t = 8.99 mean 2.65 p < 0.001). NPS use in patients with SUD is highly prevalent, particularly in the youngest age group, and associated with psychiatric comorbidity and worse prognosis. It is crucial to systematically assess NPS use and inform addiction service users with SUD of the toxic and potentially lethal side effects. Mental healthcare professionals working in addiction services should receive education and training. Cohort and longitudinal studies are needed. |
format | Online Article Text |
id | pubmed-8776073 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87760732022-01-21 Knowledge and Use of Novel Psychoactive Substances in an Italian Sample with Substance Use Disorders Dal Farra, Deborah Valdesalici, Alice Zecchinato, Giancarlo De Sandre, Alfio Saccon, Diego Simonato, Pierluigi Corazza, Ornella Martinotti, Giovanni Smith, Andrew L. Solmi, Marco Int J Environ Res Public Health Article This study aims to determine prevalence and frequency of use of novel psychoactive substances (NPS) and to identify the factors associated with NPS use in an Italian sample of patients diagnosed with substance use disorder (SUD). Prevalence and correlates of NPS knowledge and use were assessed in 185 patients with SUD in three addiction services (Padova, Belluno, Feltre) in the Veneto region with an ad-hoc designed survey. Two thirds of the samples reported knowing NPS and one third reported using them. NPS were considered by them less dangerous than “regular” substances of abuse (t = 6.06 mean 0.78, p < 0.001). Factors associated with NPS use were youth (OR = 4.81; p < 0.001), studentship (OR = 4.99; p = 0.004), subsequent mental disorders diagnosis (OR = 2.49; p = 0.027), suicide attempt history (OR = 11.67; p < 0.001), home detention (OR = 2.30; p = 0.040), residential care (OR = 5.66; p = 0.002), and polysubstance abuse (t = 8.99 mean 2.65 p < 0.001). NPS use in patients with SUD is highly prevalent, particularly in the youngest age group, and associated with psychiatric comorbidity and worse prognosis. It is crucial to systematically assess NPS use and inform addiction service users with SUD of the toxic and potentially lethal side effects. Mental healthcare professionals working in addiction services should receive education and training. Cohort and longitudinal studies are needed. MDPI 2022-01-14 /pmc/articles/PMC8776073/ /pubmed/35055743 http://dx.doi.org/10.3390/ijerph19020915 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Dal Farra, Deborah Valdesalici, Alice Zecchinato, Giancarlo De Sandre, Alfio Saccon, Diego Simonato, Pierluigi Corazza, Ornella Martinotti, Giovanni Smith, Andrew L. Solmi, Marco Knowledge and Use of Novel Psychoactive Substances in an Italian Sample with Substance Use Disorders |
title | Knowledge and Use of Novel Psychoactive Substances in an Italian Sample with Substance Use Disorders |
title_full | Knowledge and Use of Novel Psychoactive Substances in an Italian Sample with Substance Use Disorders |
title_fullStr | Knowledge and Use of Novel Psychoactive Substances in an Italian Sample with Substance Use Disorders |
title_full_unstemmed | Knowledge and Use of Novel Psychoactive Substances in an Italian Sample with Substance Use Disorders |
title_short | Knowledge and Use of Novel Psychoactive Substances in an Italian Sample with Substance Use Disorders |
title_sort | knowledge and use of novel psychoactive substances in an italian sample with substance use disorders |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776073/ https://www.ncbi.nlm.nih.gov/pubmed/35055743 http://dx.doi.org/10.3390/ijerph19020915 |
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