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Impact of untreated diabetes and COVID-19-related diabetes on severe COVID-19

Diabetes is a common comorbidity in patients with coronavirus disease (COVID-19) and contributes significantly to COVID-19 severity. We aimed to investigate the association between diabetic status and severe COVID-19. This prospective study included all COVID-19 patients admitted to our hospital, wh...

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Autores principales: Ushigome, Emi, Hamaguchi, Masahide, Sudo, Kazuki, Kitagawa, Nobuko, Kondo, Yuriko, Imai, Dan, Hattori, Tomohito, Matsui, Takaaki, Yamazaki, Masahiro, Sawa, Teiji, Fukui, Michiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776352/
https://www.ncbi.nlm.nih.gov/pubmed/35079646
http://dx.doi.org/10.1016/j.heliyon.2022.e08801
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author Ushigome, Emi
Hamaguchi, Masahide
Sudo, Kazuki
Kitagawa, Nobuko
Kondo, Yuriko
Imai, Dan
Hattori, Tomohito
Matsui, Takaaki
Yamazaki, Masahiro
Sawa, Teiji
Fukui, Michiaki
author_facet Ushigome, Emi
Hamaguchi, Masahide
Sudo, Kazuki
Kitagawa, Nobuko
Kondo, Yuriko
Imai, Dan
Hattori, Tomohito
Matsui, Takaaki
Yamazaki, Masahiro
Sawa, Teiji
Fukui, Michiaki
author_sort Ushigome, Emi
collection PubMed
description Diabetes is a common comorbidity in patients with coronavirus disease (COVID-19) and contributes significantly to COVID-19 severity. We aimed to investigate the association between diabetic status and severe COVID-19. This prospective study included all COVID-19 patients admitted to our hospital, who were divided into four groups according to their diabetic status: no diabetes, treated diabetes, untreated diabetes, and COVID-19-related diabetes. Severe COVID-19 was defined as a condition that required the use of a ventilator. Of the 114 patients included in this study, 26 had severe COVID-19. The adjusted odds ratio (OR; 95% confidence interval [CI]) for severe COVID-19 was significantly higher in the treated diabetes, untreated diabetes, and COVID-19-related diabetes groups than in the no diabetes group (OR: 5.9, 95% CI [1.2–27.9]; OR 12.6, 95% CI [1.8–86.4]; and OR: 9.3, 95% [1.1–81.4], respectively). Findings from this study showed that the risk of severe COVID-19 was increased in treated diabetes, untreated diabetes, and COVID-19-related diabetes compared to no diabetes. Furthermore, the OR for severe COVID-19 was greater in untreated diabetes and COVID-19-related diabetes than in treated diabetes.
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spelling pubmed-87763522022-01-21 Impact of untreated diabetes and COVID-19-related diabetes on severe COVID-19 Ushigome, Emi Hamaguchi, Masahide Sudo, Kazuki Kitagawa, Nobuko Kondo, Yuriko Imai, Dan Hattori, Tomohito Matsui, Takaaki Yamazaki, Masahiro Sawa, Teiji Fukui, Michiaki Heliyon Research Article Diabetes is a common comorbidity in patients with coronavirus disease (COVID-19) and contributes significantly to COVID-19 severity. We aimed to investigate the association between diabetic status and severe COVID-19. This prospective study included all COVID-19 patients admitted to our hospital, who were divided into four groups according to their diabetic status: no diabetes, treated diabetes, untreated diabetes, and COVID-19-related diabetes. Severe COVID-19 was defined as a condition that required the use of a ventilator. Of the 114 patients included in this study, 26 had severe COVID-19. The adjusted odds ratio (OR; 95% confidence interval [CI]) for severe COVID-19 was significantly higher in the treated diabetes, untreated diabetes, and COVID-19-related diabetes groups than in the no diabetes group (OR: 5.9, 95% CI [1.2–27.9]; OR 12.6, 95% CI [1.8–86.4]; and OR: 9.3, 95% [1.1–81.4], respectively). Findings from this study showed that the risk of severe COVID-19 was increased in treated diabetes, untreated diabetes, and COVID-19-related diabetes compared to no diabetes. Furthermore, the OR for severe COVID-19 was greater in untreated diabetes and COVID-19-related diabetes than in treated diabetes. Elsevier 2022-01-21 /pmc/articles/PMC8776352/ /pubmed/35079646 http://dx.doi.org/10.1016/j.heliyon.2022.e08801 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Research Article
Ushigome, Emi
Hamaguchi, Masahide
Sudo, Kazuki
Kitagawa, Nobuko
Kondo, Yuriko
Imai, Dan
Hattori, Tomohito
Matsui, Takaaki
Yamazaki, Masahiro
Sawa, Teiji
Fukui, Michiaki
Impact of untreated diabetes and COVID-19-related diabetes on severe COVID-19
title Impact of untreated diabetes and COVID-19-related diabetes on severe COVID-19
title_full Impact of untreated diabetes and COVID-19-related diabetes on severe COVID-19
title_fullStr Impact of untreated diabetes and COVID-19-related diabetes on severe COVID-19
title_full_unstemmed Impact of untreated diabetes and COVID-19-related diabetes on severe COVID-19
title_short Impact of untreated diabetes and COVID-19-related diabetes on severe COVID-19
title_sort impact of untreated diabetes and covid-19-related diabetes on severe covid-19
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8776352/
https://www.ncbi.nlm.nih.gov/pubmed/35079646
http://dx.doi.org/10.1016/j.heliyon.2022.e08801
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